Schmidt Beckurts (31 results)
More imagesArchiv der Pharmazie ( 1925 ) und Berichte der Deutschen Pharmazeutischen Gesellschaft. Band 263 des Archivs und zugleich Jhg. 35 der Berichte. 1925. - Aus dem Inhalt: H. Thoms und Karl Bergerhoff - Über Versuche zur Konstitutionserschließung des Lupanins / K. Feist und H. Bestehorn: Über den Gerbstoff des Eichenholzes. Methoden zur Gewinnung und Reinigung von Gerbstoffen / H. P. Kaufmann und E. Hansen - Schmidt : Bromometrische Versuche / J. Gadamer, M. Oberlin und A. Schoeler: Die Synthese des Aporphins / Julius Zellner: Studien über die chemischen Bestandteile heimischer Arzneipflanzen.
Pharmazie, Archiv der. - Hrsg. : Beckurts, H. u. a. - Autoren : H. Thoms und Karl Bergerhoff / K. Feist und H. Bestehorn / H. P. Kaufmann und E. Hansen - Schmidt / J. Gadamer, M. Oberlin und A. Schoeler / Julius Zellner u. a. -
Published by Verlag Chemie: Leipzig + Berlin 1925 1925
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Seller: Antiquariat Carl Wegner, Berlin, GermanyAntiquariat Carl Wegner
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Add to basketHardcover. Brauner neuerer Leinenband mit goldfarbenem Rückentitel. 1 Blatt, 750 Seiten mit einigen Textabbildungen. Ordentlich ausgeschiedenes Exemplar mit den üblichen Stempeln und Signaturen. Guter Zustand. Hrsg. von der Deutschen Apothekerschaft und der Deutschen Pharmazeutischen Gesellschaft. -- Bitte Portokosten außerhalb…EU erfragen! / Please ask for postage costs outside EU! / S ' il vous plait demander des frais de port en dehors de l ' UE! // Bitte beachten Sie auch unsere Fotos! / Please also note our photos! / Veuillez noter nos photos -- Lesen Sie etwas Schönes auf einer Bank in der Frühlingssonne! Wir haben die passende Lektüre. -- Wir kaufen Ihre werthaltigen Bücher! NatAllg.
More imagesPublished by Selbstverlag des Apotheker-Vereins/1899 1899
Seller: Antiquariat an der Linie 3, Darmstadt, GermanyAntiquariat an der Linie 3
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Add to basket8° Halbledereinband. Condition: Gut. Halbledereinband der Zeit, 20 x 14 cm, Papier altersbedingt leicht gebräunt, mit einem Autoren- und einem Sachverzeichnis. Der Band versammelt (vermutlich nach Datum des Eingangs ab November 1898) zahlreiche Aufsätze und Forschungsergebnisse zu unterschiedlichsten Themen der Pharmazie (Wirkst…offe, Systematiken, Verbindungen, Formelsammlungen). Stichworte: Apothekenwesen, Pharmazie, Sammlung, Aufsätze 723 S. Deutsch 550g.
Published by Berlin 1911
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Seller: Antiquariat C. Hoffmeister, Wolfenbüttel, GermanyAntiquariat C. Hoffmeister
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Add to basketBand 240. 8vo. 715 S. Schlichte HLwd. d. Zt., fleckig. 0,800 gr.
Published by Berlin 1894
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Seller: Antiquariat C. Hoffmeister, Wolfenbüttel, GermanyAntiquariat C. Hoffmeister
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Add to basketBand 232. 8vo. 728 S. Schlichte HLwd. d. Zt., fleckig u. bestossen. Wenige Bll. etwas stockfl. 0,800 gr.

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Paperback. Condition: New. Print on Demand. This book provides valuable insights into the detection and identification of methyl alcohol. Found in certain solvents, varnishes, and illegally produced alcoholic beverages, methyl alcohol can cause blindness when ingested, and is even fatal in some cases. The author comprehensively…explores the history of methyl alcohol poisoning, various methods for detecting it, and the chemical reactions that occur during its oxidation. The book also delves into the physiological effects and metabolism of methyl alcohol, including the excretion of formic acid in the urine. The author presents case studies of methyl alcohol poisoning and discusses the legal implications of its production and distribution. This book is a valuable resource for toxicologists, forensic scientists, and anyone concerned with the detection and prevention of methyl alcohol poisoning. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item.
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Paperback. Condition: New. Print on Demand. This book delves into the intricate nature of Scopolamin and its derivatives, providing a wealth of insights into these alkaloids that have captivated scientists for years. The author skillfully presents a comprehensive analysis of Scopolamin's chemical structure and pharmacological pr…operties, relating them to the broader context of tropane alkaloids. By examining how Scopolamin relates to other substances like Atropin and Hyoscyamine, the book unravels the connections and distinctions within this fascinating group of compounds. Through a series of experiments, the author explores the behavior of Scopolamin and its derivatives under various conditions, shedding light on their stability and reactivity. These investigations uncover valuable information about the molecular rearrangements and chemical transformations these substances undergo, deepening our understanding of their fundamental nature. The book's findings contribute to the ongoing exploration of tropane alkaloids, promising to inform future research and applications in the field of medicinal chemistry. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item.
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Paperback. Condition: New. Print on Demand. This book delves into the diverse medicinal uses of Fabiana imbricata, a plant employed for centuries by indigenous South American communities. The author, a respected scientist, meticulously investigates the plant's chemical composition, identifying crucial compounds responsible for i…ts therapeutic effects. Through the analysis of historical records and clinical observations, the book elucidates the plant's traditional applications and their relevance to contemporary medicine. The author's findings contribute to the preservation of indigenous knowledge and provide insights into the potential of natural remedies within modern healthcare. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item.
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Paperback. Condition: New. Print on Demand. This book delves into a fascinating exploration of the interactions between Chloral Hydrate - a versatile chemical compound - and various other substances, such as Stearoptens and Phenols. Recognized for its ability to induce a unique fluid state when mixed with certain compounds, Chlo…ral Hydrate unveils a world of physical and chemical phenomena when combined with different Stearoptens. Beyond its transformative effects on Stearoptens, this book also sheds light on the intriguing behavior of Stearoptens when mixed with each other and with Phenols. The author's profound analysis of these interactions exposes the intricate interplay of temperature changes, solubility, and molecular structures that govern these transformations. Furthermore, this book unearths a previously unknown anomaly in the reaction between Chloral Hydrate and Thymol, offering fresh insights into the nature of their interactions. The significance of these findings extends beyond the realm of pure chemistry, as they hold potential for practical applications in various fields. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item.

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Paperback. Condition: New. Print on Demand. This book brings a fresh perspective to the study of the Angostura bark, a key ingredient used in the production of Angostura bitters. It establishes the complex history of the plant species used for medicinal and flavouring purposes for centuries and emphasizes its continued relevance… in the present day. Exploring the chemical composition of this fascinating plant through experimental analysis, the author provides a detailed examination of the various Angostura species. The in-depth exploration of the chemical compounds offers insights into the therapeutic potential of the plant and highlights its use in traditional medicine. This comprehensive investigation of the Angostura bark deepens our understanding of its medicinal properties, contributing to ongoing research and potential advancements in natural medicine. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item.

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Paperback. Condition: New. Print on Demand. This book is an in-depth exploration of the Reten, a unique and fascinating compound found in nature. The author, a renowned expert in the field, provides a comprehensive overview of the Reten, its properties, and its various applications. The book delves into the historical significan…ce of the Reten, tracing its discovery and the subsequent research that has led to our current understanding of its chemistry and biology. The author also discusses the Reten's role in various industrial processes and its potential for future applications. With its clear and engaging writing style, this book is an essential resource for chemists, materials scientists, and anyone interested in the fascinating world of organic compounds. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item.

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Paperback. Condition: New. Print on Demand. Delving into the world of organic mercury compounds, the author examines their determination using a novel technique known as Rhodanometry. Published in 1912, this comprehensive work presents a valuable historical perspective on the subject. The primary focus of the book is on the appl…ication of Rhodanometry to analyze these compounds, providing insights into their quantitative determination. The author meticulously explains the chemistry behind this technique, discussing the reactions involved and demonstrating its effectiveness in distinguishing between different types of organic mercury compounds. Through a series of experiments, the author provides practical guidance on sample preparation and titration procedures, ensuring accurate and reliable results. This book is a valuable resource for chemists and researchers seeking a deeper understanding of organic mercury compounds and their analysis. Its contribution to the field continues to be significant, offering a foundational understanding of this important analytical technique. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item.
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Paperback. Condition: New. Print on Demand. This book delves into the rich history and multifaceted nature of the Wasserschierling, commonly known as the water hemlock. As one of the most poisonous plants in Europe, the water hemlock has garnered both fear and fascination throughout the ages. The author explores the plant's bota…nical characteristics, its historical significance, and its role in fatal poisonings. Drawing from historical records, the author delves into the cultural and medicinal uses of the water hemlock, while also providing guidance on how to distinguish it from other similar-looking plants. Ultimately, this book offers a comprehensive understanding of one of nature's most potent and dangerous plants, highlighting the importance of awareness and caution when encountering it. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item.
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Paperback. Condition: New. Print on Demand. This book explores the evolution of the historical legend of Queen Esther and its impact on Western culture. The legend originated as a Persian folktale and through centuries of retelling has been shaped by various religious and political influences, particularly during the medieval an…d Renaissance periods. Despite her fictional origins, Queen Esther has become an inspiration for countless people, embodying female strength and piety. The author presents a captivating analysis of Esther's story, examining its literary and artistic interpretations and tracing its profound influence on Western ideas about gender, power, and religious identity. This book is a valuable contribution to the study of cultural history, providing fresh insights into the enduring legacy of one of the most iconic female figures in Western civilization. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item.
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Paperback. Condition: New. Print on Demand. This book examines the varying systemic functions of the four asymmetric carbon atoms in the basic structure of the alkaloid egonine. The author traces how these functions are modified in two related compounds, and how these modifications affect the optical activity of the molecule. Th…e impact of these changes on the related compounds' chemical and physical properties is discussed in depth. The alkaloid egonine is found in the leaves of the coca plant, and is therefore an important precursor to the production of cocaine. By determining the impact of the varying asymmetric carbon atoms on the overall molecular structure, this book will be of great use to chemists and medical professionals who wish to understand more about the properties of egonine and related compounds. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item.
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Paperback. Condition: New. Print on Demand. This book is an exploration of the groundbreaking medical applications of the newly discovered element rubidium. The author begins by introducing the chemical properties of rubidium and its place among the alkali metals. The text then details the various methods for purifying rubidium…compounds, including a novel technique developed by the author. The book also examines the physiological effects of rubidium salts, focusing on their therapeutic potential in treating a wide range of ailments. By presenting a comprehensive and up-to-date account of rubidium's medicinal properties, this book provides valuable insights for researchers, clinicians, and anyone interested in the history of medicine and the development of new therapeutic agents. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item.

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Paperback. Condition: New. Print on Demand. This book provides a comprehensive analysis of the development of Abietinsäure, a crucial component in conifer resins that holds significance in various fields. The author thoroughly examines the historical evolution of research on Abietinsäure, tracing its origins from ancient obser…vations to present-day scientific understanding. The book delves into the chemistry, properties, and diverse applications of Abietinsäure, offering insights into its potential for industrial and medical uses. By exploring the role of Abietinsäure in the broader context of plant physiology and ecology, the author highlights its importance in understanding the intricate workings of the natural world. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item.

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Paperback. Condition: New. Print on Demand. This book challenges the notion that mercuric benzoate is a milder and more effective mercury-based drug. It is a chemical analysis of the ingredients and therapeutic effects of mercuric benzoate as a treatment for syphilis. The author discovered that nearly all syphilis patients treat…ed with mercuric benzoate also received sodium benzoate, and that the resulting effects were due to the latter. This book will provide insight into how 19th-century doctors treated syphilis. As a study of chemistry, pharmacy, and 19th-century medicine, this book will have wide appeal. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item.

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Paperback. Condition: New. Print on Demand. This book delves into the chemical composition of glycerin, a versatile substance with a wide range of applications. The author, a chemist, meticulously documents the results of their experiments, providing a comprehensive analysis of glycerin's behavior when subjected to various condi…tions. The book encompasses both theoretical explanations and practical observations, offering valuable insights for those working with glycerin in various fields. Through detailed experiments, the author elucidates the complex interactions of glycerin with other substances, revealing its unique properties and potential for further exploration. This book serves as a valuable resource for scientists, researchers, and anyone seeking a deeper understanding of the intricate chemistry of glycerin. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item.

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Paperback. Condition: New. Print on Demand. This book explores the chemical composition of Thiosinamin, a substance discovered in 1856. The author sets out to determine the structure of Thiosinamin's constituent atoms and the nature of the forces that hold them together. 19th-century chemistry had already classified Thiosinamin…as a member of the class of compounds known as thiocarbamides. However, the exact composition of these compounds was not known at the time. After a series of groundbreaking experiments, the author determines that the chemical formula for Thiosinamin is C4H8N2S. This discovery paves the way for further research on the chemical structure of related compounds and advances the field of organic chemistry. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item.

Language: German
Published by Berlin, Selbstverlag des Deutschen Apotheker-Vereins, 1890
Seller: Antiquariat Matthias Drummer, Berlin, GermanyAntiquariat Matthias Drummer
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Add to basket730 Seiten, Die Zeitschrift erschien zuerst als Archiv des Apothekervereins im nördlichen Teutschland 1822 bis 1834; dann als Archiv der Pharmacie, zweite Reihe von 1835 bis 1872, dann als Archiv der Pharmacie, dritte Reihe von 1873 bis 1944. Mit zahlreichen Beiträgen verschiedener Autorinnen und Autoren, Bücherschau, Sachverzei…chnis und Schriftstellerverzeichnis. Mit rundum gesprengeltem Schnitt. Der Rücken stärker, die Einbanddeckel und Einbandkanten etwas beschabt, das Papier gebräunt, der Rücken an der oberen Kante mit kleinem Einriss, sonst und insgesamt ordentliches Exemplar Sprache: Deutsch Gewicht in Gramm: 744 Original-Halbleder, 14x21cm, Zustand: 3.

Language: German
Published by Berlin, Selbstverlag des Deutschen Apotheker-Vereins, 1892
Seller: Antiquariat Matthias Drummer, Berlin, GermanyAntiquariat Matthias Drummer
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Add to basket719 Seiten, Die Zeitschrift erschien zuerst als Archiv des Apothekervereins im nördlichen Teutschland 1822 bis 1834; dann als Archiv der Pharmacie, zweite Reihe von 1835 bis 1872, dann als Archiv der Pharmacie, dritte Reihe von 1873 bis 1944. Mit zahlreichen Beiträgen verschiedener Autorinnen und Autoren, Bücherschau, Sachverzei…chnis und Schriftstellerverzeichnis. Mit rundum gesprengeltem Schnitt. Der Rücken stärker, die Einbanddeckel und Einbandkanten etwas beschabt, das Papier gebräunt, sonst und insgesamt ordentliches Exemplar Sprache: Deutsch Gewicht in Gramm: 768 Original-Halbleder, 14x21cm, Zustand: 3.

Published by Berlin: Selbstverlag des Deutschen Apotheker-Vereins 1899-1912. 1899
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Seller: Antiquariat Kretzer, Kirchhain-Emsdorf, GermanyAntiquariat Kretzer
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Add to basketCondition: Gut. 12 Bände. Bände 238-245 mit Rückensignaturen. Einbände leicht berieben. Einige Blätter stellenweise minimal stockfleckig. Ansonsten sehr gut bis gut erhaltenes Exemplar. Sprache: Deutsch Gewicht in Gramm: 9500 8° (17,5-22,5 cm). Goldgeprägte Orig.-Leinenbände. [Hardcover / fest gebunden].

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Paperback. Condition: New. Print on Demand. This book examines the 19th-century American fascination with the Mexican War and its long-term social and cultural impacts. The author explores the various factors, including national ambition, territorial greed, and jingoism, that drove the US to wage war with Mexico, and discusses h…ow this conflict shaped American identity and sowed the seeds of future conflicts, including the American Civil War. This book will appeal to scholars and general readers interested in American history, the Mexican-American War, and the enduring legacy of war and empire in the United States. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item.

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Paperback. Condition: New. Print on Demand. This book delves into the chemical composition of chrysarobin, a valuable substance used in treating skin conditions like psoriasis and eczema. The author, a renowned expert in the field, meticulously examines the components of this natural remedy, tracing their origins and studying th…eir properties. The book provides a comprehensive overview of the research conducted on chrysarobin since its discovery in the 19th century. It explores the complex relationships between the various substances found within chrysarobin, including anthraquinones and their derivatives. The author sheds light on how these components contribute to the therapeutic effects of chrysarobin, enhancing our understanding of this natural medicine. Through a series of experiments, the author unveils new insights into the behavior of chrysarobin under different conditions, revealing its transformation when exposed to air and its interactions with solvents. The book also delves into the challenges of isolating and purifying chrysarobin's components, emphasizing the importance of careful methodology in studying this intricate substance. This book is a valuable resource for scientists, researchers, and practitioners in the fields of chemistry, dermatology, and natural medicine. It offers a deeper understanding of chrysarobin's composition and properties, advancing our knowledge of this remarkable natural remedy and its potential applications in treating skin disorders. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item.
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Paperback. Condition: New. Print on Demand. This book explores the chemical nature of a complex healing substance known as chrysarobin, found in the Goa powder produced by the araroba tree in Brazil. The author presents the results of extensive chemical investigations into the composition of this powder, which has been utilized…for centuries in traditional medicine, yet remained poorly understood. The author successfully identified and characterized the various components of chrysarobin, providing new insights into its structure and properties. This research not only enhances our knowledge of the tree's healing properties but also lays the groundwork for future advancements in the field of natural medicine. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item.

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Paperback. Condition: New. Print on Demand. This book presents a comprehensive analysis of the morphology, taxonomy, and phytochemistry of the genus Ononis L., which comprises around 70 species distributed across the globe. The author delves into the intricate relationships between the various species, employing advanced techniq…ues such as molecular phylogenetics and comparative micromorphology. Through detailed descriptions, illustrations, and distribution maps, the book provides a valuable resource for botanists, taxonomists, and ecologists seeking to understand the diversity and evolution of this fascinating genus. The author's meticulous research sheds light on the complex evolutionary history of Ononis L., offering insights into the processes that have shaped its current distribution and morphological characteristics. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item.

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Paperback. Condition: New. Print on Demand. This book presents the results of the authorsâ study, which seeks to identify and quantify the presence of arsenic in human physiological processes. Drawing from historic foundational studies and their own experimental findings, the authors re-evaluate the conclusions posited by earlie…r researchers. The authors examine not only the presence of arsenic in the human body but also its origins, elimination from the body, and its effects and interactions with various salts. Ultimately, this book not only serves as a survey of current knowledge regarding arsenic in the human body but also opens avenues for further research in this area. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item.

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Paperback. Condition: New. Print on Demand. This book enhances our understanding of quaternary alkaloids through a foundation of natural product chemistry. The author draws upon various disciplines, ranging from chemistry to biology, to provide a detailed examination of the diverse structural features and pharmacological propert…ies of these alkaloids. Through case studies and examples, the book explores the historical significance of quaternary alkaloids in the development of pharmaceuticals, their mechanisms of action, and their potential use in treating various disorders. The author provides a comprehensive analysis of the current state of research on quaternary alkaloids, making this book an indispensable resource for researchers, students, and professionals in the field. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item.

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Paperback. Condition: New. Print on Demand. This book explores the means of preserving the active components of plant-based remedies during their preparation into tinctures and extracts. The author emphasizes the importance of preventing the degradation of the active components, or glycosides, due to factors such as enzymes and…plant acids. The book's insights are particularly valuable as many plants used in traditional medicine contain glycosides and their preservation is essential for maintaining the efficacy of these remedies. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item.
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Seller: Forgotten Books, London, United KingdomForgotten Books
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US$ 29.56
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Paperback. Condition: New. Print on Demand. This book explores the chemical nature of Timbà , a Brazilian fish poison derived from the plant Paullinia pinnata. The author, a renowned pharmacologist, delves into the history of Timbà 's use by indigenous populations, examining its toxic effects on fish and its potential impact on…human health. Through meticulous research, the author identifies the active components responsible for Timbà 's toxicity, providing a comprehensive analysis of their chemical properties and pharmacological actions. The book contributes to our understanding of natural toxins and their significance in traditional fishing practices, offering valuable insights for researchers in toxicology, pharmacology, and environmental science. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item.