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Published by Springer Nature B.V., 2023
ISBN 10: 9811982503 ISBN 13: 9789811982507
Language: English
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Published by Springer Nature B.V., 2023
ISBN 10: 9811982503 ISBN 13: 9789811982507
Language: English
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Condition: Very Good. [ No Hassle 30 Day Returns ][ Ships Daily ] [ Underlining/Highlighting: NONE ] [ Writing: NONE ] [ Edition: Reprint ] Publisher: Springer Pub Date: 3/2/2023 Binding: Hardcover Pages: 384 Reprint edition.
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Add to basketPaperback. Condition: Brand New. 396 pages. 9.21x6.14x0.83 inches. In Stock.
Published by Springer Nature B.V. Mär 2023, 2023
ISBN 10: 9811982503 ISBN 13: 9789811982507
Language: English
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Published by Elsevier Science & Technology, 2021
ISBN 10: 0323897754 ISBN 13: 9780323897754
Language: English
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Published by Springer Verlag, Singapore, Singapore, 2021
ISBN 10: 9811568170 ISBN 13: 9789811568176
Language: English
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Paperback. Condition: new. Paperback. This book provides up-to-date information on bioinformatics tools for the discovery and development of new drug molecules. It discusses a range of computational applications, including three-dimensional modeling of protein structures, protein-ligand docking, and molecular dynamics simulation of protein-ligand complexes for identifying desirable drug candidates. It also explores computational approaches for identifying potential drug targets and for pharmacophore modeling. Moreover, it presents structure- and ligand-based drug design tools to optimize known drugs and guide the design of new molecules. The book also describes methods for identifying small-molecule binding pockets in proteins, and summarizes the databases used to explore the essential properties of drugs, drug-like small molecules and their targets. In addition, the book highlights various tools to predict the absorption, distribution, metabolism, excretion (ADME) and toxicity (T) of potential drug candidates. Lastly, it reviews in silico tools that can facilitate vaccine design and discusses their limitations. It also explores computational approaches for identifying potential drug targets and for pharmacophore modeling. Moreover, it presents structure- and ligand-based drug design tools to optimize known drugs and guide the design of new molecules. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.
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Published by Springer Verlag, Singapore, Singapore, 2021
ISBN 10: 981155532X ISBN 13: 9789811555329
Language: English
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Paperback. Condition: new. Paperback. This book discusses a broad range of basic and advanced topics in the field of protein structure, function, folding, flexibility, and dynamics. Starting with a basic introduction to protein purification, estimation, storage, and its effect on the protein structure, function, and dynamics, it also discusses various experimental and computational structure determination approaches; the importance of molecular interactions and water in protein stability, folding and dynamics; kinetic and thermodynamic parameters associated with protein-ligand binding; single molecule techniques and their applications in studying protein folding and aggregation; protein quality control; the role of amino acid sequence in protein aggregation; muscarinic acetylcholine receptors, antimuscarinic drugs, and their clinical significances.Further, the book explains the current understanding on the therapeutic importance of the enzyme dopamine beta hydroxylase; structural dynamics and motions in molecularmotors; role of cathepsins in controlling degradation of extracellular matrix during disease states; and the important structure-function relationship of iron-binding proteins, ferritins. Overall, the book is an important guide and a comprehensive resource for understanding protein structure, function, dynamics, and interaction. This book discusses a broad range of basic and advanced topics in the field of protein structure, function, folding, flexibility, and dynamics. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.
Published by Taylor & Francis Ltd, London, 2025
ISBN 10: 1032854766 ISBN 13: 9781032854762
Language: English
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Add to basketHardcover. Condition: new. Hardcover. This book explores the pharmacological potentials of various classes of plant secondary metabolites. The initial chapter introduces the chemical diversity, biosynthesis pathways, and ecological functions of plant secondary metabolites. It discusses the pivotal role of transcription factors in regulating their production. Furthermore, the book examines the specific classes of secondary metabolites, such as phenolic compounds, terpenes, and anthocyanins, highlighting their properties and various applications across the food, cosmetics, and pharmaceutical industries. This book delves into emerging areas such as plant metabolites as nutraceuticals, the utilization of horticultural and vegetable crops for secondary metabolite production, and the exploration of staple crops for health improvements. The chapters discuss the applications of fungal endosymbionts and algal sources in shaping plant metabolite compositions. The chapters further review innovative techniques, such as hairy root engineering and recombinant systems, for enhancing metabolite production. The book concludes with a detailed overview of methods for isolating and identifying secondary metabolites. This book is an essential resource for students, researchers, and professionals of ethnopharmacology, pharmaceutical sciences, botany, and biomedical sciences.Key Features:Covers various classes of plant secondary metabolites and their pharmacological potentialsExplores the role of transcription factors in controlling secondary metabolite production in plantsDiscusses secondary metabolites from horticultural and vegetable crops, highlighting their pharmaceutical applicationsPresents techniques like hairy root engineering and recombinant systems for enhancing metabolite productionExamines lichen metabolites and their applications in human health, as well as metabolites from gymnosperms This book explores the pharmacological potential of plant secondary metabolites, discussing their diversity, biosynthesis pathways, innovative production techniques, and applications in food, cosmetics, and pharmaceutical industries. This book is useful for researchers of ethnopharmacology, pharmaceutical sciences, and biomedical sciences. Shipping may be from our Sydney, NSW warehouse or from our UK or US warehouse, depending on stock availability.
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Published by Springer Verlag, Singapore, Singapore, 2020
ISBN 10: 981155529X ISBN 13: 9789811555299
Language: English
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Hardcover. Condition: new. Hardcover. This book discusses a broad range of basic and advanced topics in the field of protein structure, function, folding, flexibility, and dynamics. Starting with a basic introduction to protein purification, estimation, storage, and its effect on the protein structure, function, and dynamics, it also discusses various experimental and computational structure determination approaches; the importance of molecular interactions and water in protein stability, folding and dynamics; kinetic and thermodynamic parameters associated with protein-ligand binding; single molecule techniques and their applications in studying protein folding and aggregation; protein quality control; the role of amino acid sequence in protein aggregation; muscarinic acetylcholine receptors, antimuscarinic drugs, and their clinical significances.Further, the book explains the current understanding on the therapeutic importance of the enzyme dopamine beta hydroxylase; structural dynamics and motions in molecularmotors; role of cathepsins in controlling degradation of extracellular matrix during disease states; and the important structure-function relationship of iron-binding proteins, ferritins. Overall, the book is an important guide and a comprehensive resource for understanding protein structure, function, dynamics, and interaction. This book discusses a broad range of basic and advanced topics in the field of protein structure, function, folding, flexibility, and dynamics. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.
Seller: Ria Christie Collections, Uxbridge, United Kingdom
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