Gene Expression Muscle (33 results)

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Language: English
Published by VDM Verlag Dr. Müller|VDM Verlag Dr. Müller e.K., 2013
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Condition: New. The development and maintenance of muscle cells is controlled by complex regulatory networks involving epigenetic marks and transcription factors. While histone modifications influence the compaction of chromatin and consequently the accessibility of DNA, t.

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Taschenbuch. Condition: Neu. Regulatory Networks of Gene Expression in Heart and Skeletal Muscle Cells | The Role of Histone Modifications and Transcription Factors in Muscle Cell Development and Maintenance | Jenny J. Fischer | Taschenbuch | Kartoniert / Broschiert | Englisch | 2013 | VDM Verlag Dr. Müller | EAN 9783836483735 |… Verantwortliche Person für die EU: OmniScriptum GmbH & Co. KG, Bahnhofstr. 28, 66111 Saarbrücken, info[at]akademikerverlag[dot]de | Anbieter: preigu.

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Paperback. Condition: Brand New. reprint edition. 444 pages. 9.45x6.61x1.01 inches. In Stock.

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Taschenbuch. Condition: Neu. Neuware - This volume contains the edited transcript of an interdisci plinary colloquium held at Totts Gap Medical Research Laboratories, Bangor, Pennsylvania on October 12-14, 1983 under the sponsorship of the Muscular Dystrophy Association. The aim was to illuminate the pathogenic mechanism of Duch…enne Muscular Dystrophy through a synthesis of available data on gene expression in muscle. In the informal give and take ot the collo quium, the participants found themselves engaged in mutual education and enlightenment as they attempted to put together what is known and to highlight what is not known about the subject. Significant research into muscle as a tissue and muscle disease began only about 50 years ago although the description of muscular dystrophy by Guillaume Benjamin Amand Duchenne de Boulogne had been published in 1862. By 1943 it was clear that Duchenne muscular dystrophy was an X-linked genetic disorder. Up to the present, however, the offending gene has not been identified although its location on the short arm of the X chromosome has been approximately determined. The gene product associated with the initial disturbance in skeletal muscle has also remained elusive up to now. Moreover, investigations into the mechanisms of the muscle degeneration have been hampered by ignorance of the fundamental phenotypic expression of the genetic disorder.

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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - LPA is a component of oxidized low density lipoproteins (oxLDL) which has been shown to accumulate in human atherosclerotic plaques. Tissue factor (TF) is the principal initiator of blood coagulation. Tissue factor upregulation in athero…sclerotic plaque can lead to undesirable vascular thrombosis. The generation of reactive oxygen species (ROS), which act as signaling molecules in the vascular system, is enhanced in response to injury and has been associated with a procoagulant state and the progression of atherosclerotic disease. Oxidative stress might contribute to the increased expression of pro atherosclerotic genes at sites of vascular injury, including TF. Little is known about the regulation of TF by LPA in smooth muscle cells (SMC) which is a major player in the process of atherosclerosis. Data generated by this study demonstrate that LPA markedly induces TF expression in rat aorta smooth muscle cells (RASMCs) and human aorta smooth muscle cells (HASMCs). The signaling pathways involved are multiple.

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Taschenbuch. Condition: Neu. Lysophosphatidic Acid Induction Of Tissue Factor Gene Expression | A Molecular Study In Vascular Smooth Muscle Cells | Essam Laag | Taschenbuch | 96 S. | Englisch | 2010 | LAP LAMBERT Academic Publishing | EAN 9783838381374 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42,…22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu Print on Demand.