Carbohydrate Recognition: Biological Problems, Methods, and Applications (Wiley Series in Drug Discovery and Development)

Binghe Wang; Geert-Jan Boons

ISBN 10: 0470592079 / ISBN 13: 9780470592076

Published by Wiley, 2011

About this Item

Hardcover, x + 430pp + 8 pages of glossy colour plates, NOT ex-library. Limited signs of gentle wear, book is clean and bright with unmarked text, free of inscriptions and stamps, firmly bound. Issued without a dust jacket. -- An extensive resource that delves into the critical role of carbohydrates in biological systems, focusing on how carbohydrates are recognized and processed by different proteins and molecules. This book covers a broad range of topics related to the recognition of carbohydrates, from the fundamental chemistry of glycans to their diverse biological functions and applications in biotechnology and medicine. It addresses the latest research methods and applications, making it an essential reference for anyone involved in carbohydrate research or related fields. -- Contents: 1 Mammalian Glycan Biosynthesis: Building a Template for Biological Recognition / M. Adam Meledeo, Venkata D. P. Paruchuri, Jian Du, Zhiyun Wang & Kevin J. Yarema; 2 Roles of Carbohydrate Binding in Cell Adhesion and Inflammation / Ken Kitajima & Chihiro Sato; 3 Role of Carbohydrates in Viral Infections / Gillian M. Air; 4 Role of Carbohydrates in Bacterial Infections / Roland J. Pieters; 5 Roles of Carbohydrate Binding in Fertilization / David J. Miller; 6 Carbohydrate Biomarkers / Yunfeng Cheng, Nanting Ni, Hanjing Peng, Shan Jin & Binghe Wang; 7 Galectins and Their Role in Various Biological Processes / Sarika Saraswati, Ashley Stanley Block & Alan B. Diekman; 8 Glycoimmunology / Ani Grigorian, Barbara Newton & Michael Demetriou; 9 Tools For Glycomics: Glycan and Lectin Microarrays / Christopher Campbell & Jeff Gildersleeve; 10 Combinatorial Biosynthesis of Complex Carbohydrates / Hai Yu & Xi Chen; 11 Mass Spectrometry in Carbohydrate Sequencing and Binding Analysis / Gregory O. Staples & Joseph Zaia; 12 Synthetic Lectin Mimics Artificial Carbohydrate Receptors / Xiaochuan Yang, Yunfeng (Jerry) Cheng & Binghe Wang; 13 Lectin Binding and Its Structural Basis / Annabelle Varrot, Bertrand Blanchard & Anne Imberty; 14 Multivalency in Carbohydrate Binding / Mark L. Wolfenden & Mary J. Cloninger; 15 Carbohydrate Binding Agents: Potential Therapeutics with Multiple Inhibitory Actions Against Enveloped Viruses / K.O. François & J. Balzarini; 16 Informatics for Glycobiology and Glycomics / Kiyoko F. Aoki-Kinoshita; Index.

Seller Inventory # 010303

Bibliographic Details

• Title: Carbohydrate Recognition: Biological Problems, Methods, and Applications (Wiley Series in Drug Discovery and Development)
• Publisher: Wiley
• Publication Date: 2011
• Language: English
• ISBN 10: 0470592079
• ISBN 13: 9780470592076
• Binding: Hardcover
• Edition: 1st Edition
• Condition: Very Good

About this title

Synopsis

This book contains contributions from interdisciplinary scientists to collectively address the issue of targeting carbohydrate recognition for the development of novel therapeutic and diagnostic agents. The book covers (1) biological problems involving carbohydrate recognition, (2) structural factors mediating carbohydrate recognition, (3) design and synthesis of lectin mimics that recognize carbohydrate ligands with high specificity and affinity, and (4) modulation of biological and pathological processes through carbohydrate recognition.

About the Author

BINGHE WANG, PHD, is Professor and Chair of the Department of Chemistry at Georgia State University as well as Georgia Research Alliance Eminent Scholar in Drug Discovery. He is Editor-in-Chief of the journal Medicinal Research Reviews, Series Editor for the Wiley Series in Drug Discovery and Development, and editor of Drug Delivery: Principles and Applications and Chemosensors: Principles, Strategies, and Applications (Wiley).

GEERT-JAN BOONS, PHD, is Franklin Professor of Chemistry and Professor in the Complex Carbohydrate Research Center at the University of Georgia. He is on the editorial boards of several journals on carbohydrates, including European Journal of Chemistry and Journal of Carbohydrate Chemistry, and is also coeditor of Carbohydrate-Based Immunotherapies and Vaccines (Wiley).