Title: Carcinogenicity, the Design, Analysis and Interpretation of Long-term Animal Studies, ILSI MONOGRAPH
Publisher: Springer-Verlag
Publication Date: 1988
Language: English
ISBN 10: 3540183019
ISBN 13: 9783540183013
Binding: Hardcover
Edition: First Edition
Condition: New
Dust Jacket Condition: No Jacket

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Synopsis

Critical issues in the design, evaluation and interpretation of long-term animal carcinogenicity studies are addressed in this volume. The presentations are by top pathologists, toxicologists and statisticians in the USA, Canada and Europe, representing industry, academia and regulatory agencies. The discussions involve controversial as well as conventional issues and are presented from statistical and biological or toxicological perspectives. Although more work has been done and published on long-term animal carcinogenicity studies than in any other phase of chemical or drug safety assessment, many issues still remain unresolved. Some solutions have been proposed, but in many instances they have not proven to be completely remedial. This volume continues important discussion of these issues and proposed solutions, and should be of interest to scientists engaged in long-term animal carcinogenicity testing.

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