Cell Engineering and Regeneration (Hardcover)

Language: English

Published by Springer International Publishing AG, Cham, 2020

3319088300 / 9783319088303

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  • Hardcover
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Hardcover. This reference work presents the origins of cells for tissue engineering and regeneration, including primary cells, tissue-specific stem cells, pluripotent stem cells and trans-differentiated or reprogrammed cells. There is particular emphasis on current understanding of tissue regeneration based on embryology and evolution studies, including mechanisms of amphibian regeneration. The book covers the use of autologous versus allogeneic cell sources, as well as various procedures used for cell isolation and cell pre-conditioning , such as cell sorting, biochemical and biophysical pre-conditioning, transfection and aggregation. It also presents cell modulation using growth factors, molecular factors, epigenetic approaches, changes in biophysical environment, cellular co-culture and other elements of the cellular microenvironment. The pathways of cell delivery are discussed with respect to specific clinical situations, including delivery of ex vivo manipulated cells via local and systemic routes, as well as activation and migration of endogenous reservoirs of reparative cells. The volume concludes with an in-depth discussion of the tracking of cells in vivo and their various regenerative activities inside the body, including differentiation, new tissue formation and actions on other cells by direct cell-to-cell communication and by secretion of biomolecules. This reference work presents the origins of cells for tissue engineering and regeneration, including primary cells, tissue-specific stem cells, pluripotent stem cells and trans-differentiated or reprogrammed cells. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.

Seller Inventory # 9783319088303

Title
Cell Engineering and Regeneration (Hardcover)
Author
Jeffrey M. Gimble
Publisher
Springer International Publishing AG, Cham
Publication year
2020
Condition
new
Binding
Hardcover
Language
English
ISBN 10
3319088300
ISBN 13
9783319088303
Edition
1st Edition

Grand Eagle Retail

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