Chiral Separations and Stereochemical Elucidation: Fundamentals, Methods, and Applications

An expert resource for chemists using stereochemical analysis methods

In Chiral Separations and Stereochemical Elucidation: Fundamentals, Methods, and Applications, a team of distinguished researchers delivers a robust and authoritative discussion of the theoretical fundamentals of chiral separation, the most commonly used chiral selectors, and stereochemical elucidation methods. The book offers expert discussions of a variety of chiral separation methods by gas chromatography (GC), supercritical fluid chromatography (SFC), capillary electrophoresis (CE), and liquid chromatography (LC).

The authors also describe several methods for stereochemical elucidation, including X-ray crystallography, nuclear magnetic resonance spectroscopy, and chiroptical methods. The explored material is ideal for practicing chemists seeking a resource to help them guide method development and optimization or to explain quality control-complements during target compound production.

Readers will also find:

• A thorough introduction to the most important advances and applications in LC, GC, CE, SFC, and preparative chromatography
• Comprehensive explorations of the role of 2D-LC for chiral separation methods development and applications
• Practical discussions of the design, mechanisms, and applications of the most commonly used chiral selectors
• Fulsome treatments of the theoretical backgrounds, advantages, limitations, and applications of stereochemical elucidation methods

Perfect for academic and industrial chemists specially in organic, analytical chemistry and pharmaceutical analysis. Chiral Separations and Stereochemical Elucidation: Fundamentals, Methods, and Applications will also benefit biochemists, environmental analysts, forensic and medicinal chemists as well as natural product chemists and those involved with stereochemistry or structural elucidation.

Quezia Bezerra Cass, PhD, is a Full Professor of Chemistry at Universidade Federal de São Carlos, São Carlos, SP, Brazil.

Maria Elizabeth Tiritan, PhD, is an Assistant Professor of Organic Chemistry at Universidade do Porto, Porto, Portugal.

João Marcos Batista Junior, PhD, is an Assistant Professor of Chemistry at Universidade Federal de São Paulo, São José dos Campos, SP, Brazil.

Juliana Cristina Barreiro, PhD, is a Researcher in Chemistry at Universidade de São Paulo, São Carlos, SP, Brazil.