Crystallographic and Modeling Methods in Molecular Design

C. E. Bugg and S. E. Ealick (editors)

ISBN 10: 0387972102 / ISBN 13: 9780387972107

Published by Springer-Verlag, New York, NY, 1990

About this Item

First Edition USA (1990) , unstated. First Printing indicated by a complete numerical sequence. Fine: flawless; the binding is square and secure; the text is clean. Free of any creased or dog-eared pages in the text. Free of ownership names, dates, addresses, notations, inscriptions, stamps, or labels. A handsome, like-new copy, structurally sound and tighly bound, showing no discernible imperfections. Bright and clean. Corners sharp. Appears unopened and unread. NOT a Remainder, Book-Club, or Ex-Library. 8vo. (9.5 x 6.3 x 0.75 inches) . Illustrated with 106 figures, graphs, tables, charts in black & white. Language: English. Weight: 21.1 ounces. Hardback: No DJ 'as issued'. ; Large 8vo 9" - 10" tall; xvii, 269 pages.

Seller Inventory # 57994

Bibliographic Details

• Title: Crystallographic and Modeling Methods in Molecular Design
• Publisher: Springer-Verlag, New York, NY
• Publication Date: 1990
• Language: English
• ISBN 10: 0387972102
• ISBN 13: 9780387972107
• Binding: Hardcover
• Edition: First Edition; First Printing.
• Condition: Near Fine
• Dust Jacket Condition: No Dust Jacket As Issued

About this title

Synopsis

This book contains the papers that were presented at the "Crystallo­ graphic and Modeling Methods in Molecular Design Symposium" in Gulf Shores, Alabama, April 30 to May 3, 1989. During the past few years, there has been a burst of activity in this area, especially related to drug design and protein engineering projects. The purpose of the symposium and this book is to provide an up-to­ date review of the most recent experimental and theoretical approaches that are being used for molecular design. The book covers several re­ cent examples of approaches for using crystallography in conjunction with forefront modeling methods for guiding the development of en­ zyme inhibitors and of peptides and proteins with modified biological and physical properties. In addition, this book contains discussions of new approaches for combining crystallographic data and advanced computational techniques for aiding in the design of enzyme inhibitors and other compounds that bind to selected biological targets. This book is therefore of interest not only to molecular biologists and biochem­ ists, but is stimulating reading for anyone involved in structural biol­ ogy, pharmaceutical chemistry, enzymology, protein engineering, and biotechnology. The meeting was the third in a series of symposia initiated and spon­ sored by the Department of Biochemistry, University of Alabama at Birmingham.