The Effect in Stomach of Ionizing Radiation on Acid Secretion, Potential, Adenosine Triphosphate and Phosohocreatine in Comparison to Spleen; USNRDL-TR-980 21 February 1966

28 pages per DD Form 1473. Plus 2 pages for the form. UNCLASSIFIED. Very Scarce. Ex-library with usual library markings. Mailing information on the back cover. Results using an In Vitro rat stomach preparation indicate that gastric acid secretion was stimulated through neurological pathways and induced by both handling and irradiation. The changes in acid secretion occurred independently of alterations in the sodium-potassium dependent potential across the stomach. Despite the two functional radiation effects, there were no gross changes in phosphorylative metabolism in rat stomach, otherwise adenosinetriphosphate and phosphocreatine would have been affected. At the same time, there was the expected irradiation change in spleen ATP, but the spleen phosphocreatine remained unchanged. The latter was a new observation which put in question some aspects of the current cellular theory of splenic irradiation effects. The United States Naval Radiological Defense Laboratory (NRDL) was an early military lab created to study the effects of radiation and nuclear weapons. The facility was based at the Hunter's Point Naval Shipyard in San Francisco, California. The NRDL was formed in 1946 to manage testing, decontamination, and disposition of US Navy ships contaminated by the Operation Crossroads nuclear tests in the Pacific. A number of ships that survived the atomic detonations were towed to Hunter's Point for detailed study and decontamination. The first use of radioactive materials at NRDL predated the issuing of licenses by the Atomic Energy Commission, but the AEC later issued licenses for a broad spectrum of radioactive materials to be used in research at the NRDL. Radioactive materials specific to nuclear weapon testing were exempted from AEC licensing.…