Rubbing and toning overall, brief sunning to the joints, signed by a previous owner on the front verso, and a blind ex-libris stamp on the half-title. Internal pages clean and unmarked. Photos on request. International shipping billed at cost. ; Methods In Cell Biology; 8vo 8" - 9" tall; 670 pages.

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Bibliographic Details

Title

Functional Organization of the Nucleus, Vol. 35 A Laboratory Guide

Publisher

Academic Press

Publication Date

1992

Language

English

ISBN 10

0123219205

ISBN 13

9780123219206

Binding

Plastic comb binding

Edition

First Edition.

Condition

Very Good+

Dust Jacket Condition

No Dust Jacket

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About this title

Synopsis

The complex problem of the relationship between nuclear structure and function demands a multidisciplinary, multifaceted approach. This laboratory guide is designed for researchers, from graduate students to professionals, who need detailed protocols and general discussions on a broad range of techniques. The volume presents a selection of different methodological approaches for the analysis of nuclear structure and function--from cytological to molecular to genetic. These include visualization of nucleic acid sequences using hybridization probes, visualization of proteins using immunological probes, isolation of chromatin fractions, mapping in vitro protein*b1DNA interactions, reconstitution of functional templates and nuclear substructures, and genetic approaches to identifying and characterizing chromosomal components.

Features two full-color plates illustrating in situ hybridization methods
Presents, for the first time in one place, varied experimental approaches for studying nuclear structure and function including
Analysis of macromolecular interactions
Reconstitution of functional complexes
Visualization of nucleic acids and proteins
Genetic methods

"About this title" may belong to another edition of this title.

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