Genome Sequencing Technology and Algorithms

The 2003 completion of the Human Genome Project was just one step in the evolution of DNA sequencing. Now from a who's who of pioneers in the field comes the latest genome sequencing and assembly advances that are redefining the field. This trail-blazing book gives researchers, unparalleled access to state-of-the-art DNA sequencing technologies, new algorithmic sequence assembly techniques, and emerging methods for both resequencing and genome analysis that together form the most solid foundation possible for tackling experimental and computational challenges in the genome sciences today. Including critiques of existing techniques, this far-reaching resource offers researchers assistance in achieving more rapid and accurate DNA sequencing and developing the next generation of high-throughput methods and devices.

Sun Kim is assistant professor and associate director of bioinformatics at Indiana University's Center for Genomics and Bioinformatics. Dr. Kim earned his Ph.D. in Computer Science at the University of Iowa. Elaine R. Mardis is assistant professor at Washington University School of Medicine and co-director of the university's Genome Sequencing Center. She received her Ph.D. in biochemistry from the University of Oklahoma. Haixu Tang is an assistant professor of informatics at Indiana University. He received his Ph.D. in computational biology from the Shanghai Institute of Biochemistry, China.