A guide to techniques in mouse development. It covers various techniques for the cryopreservation of gametes and embryos, production of transgenic and null (knockout) animals (use of ES cells), generation of conditional/inducible mutant animals, use of gene-trap mutagenesis, analysis of allele-specific expression, and more. Num Pages: 536 pages, black & white tables, figures. BIC Classification: PSAK; PSD; PSF; PSVW7. Category: (P) Professional & Vocational. Dimension: 227 x 153 x 28. Weight in Grams: 856. . 2010. 1st Edition. paperback. . . . .

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Bibliographic Details

Title: Guide to Techniques in Mouse Development, Part A: Mice, Embryos, and Cells
Publisher: Academic Press
Publication Date: 2010
Language: English
ISBN 10: 0123848830
ISBN 13: 9780123848833
Binding: Soft cover
Edition: 1st Edition
Condition: New

About this title

Synopsis

This volume comprehensively covers new technologies and methodologies that have appeared for the study of mouse development.

First of a 2 part update of volume 225, Guide to Techniques in Mouse Development, edited by P.M. Wassarman and M.L. DePamphilis and published in 1993
Comprehensively covers:

new techniques for the cryopreservation of gametes and embryos
production of transgenic and null (knockout) animals (use of ES cells)
generation of conditional/inducible mutant animals
use of gene-trap mutagenesis
analysis of allele-specific expression
use of new reporter constructs
humanizing of transgenic animals
transcript profiling of mouse development, imaging of mouse development
rederivation of animals and use of mouse genomics

About the Author

Philippe Soriano,is Professor of Cell, Developmental & Regenerative Biology and Professor of Oncological Sciences, Icahn School of Medicine at Mount Sinai, NY, USA

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