Softcover with pink background on binding Black and red print on spine. Black ,red and white on front cover. No spine creases. Slight flair at lower front corner. Tight, sound and unmarked. 327 pages iincluding index. One of the publisher's "Practical Approach Series".

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Bibliographic Details

Title: HIV: A Practical Approach, Volume 2: Biochemistry, Molecular Biology, and Drug Discovery (Practical Approach Series)
Publisher: IRL Press / Oxford University, New York, New York
Publication Date: 1995
Language: English
ISBN 10: 019963498X
ISBN 13: 9780199634989
Binding: Trade Paperback
Edition: 1st Edition
Condition: As New
Dust Jacket Condition: No Jacket

About this title

Synopsis

HIV Volume 2 explores the biochemistry and molecular biology of HIV. Methods for cloning and expressing most of the viral proteins are described as well as assays for studying enzyme function in vitro. It also includes a section on recent approaches to drug discovery.

Contents: The HIV life cycle; Reverse transcriptase; Ribonulease H; Integrase; Protease; Expression of gag, envelope and other HIV antigens using Bacculovirus; Envelope expression and purification; HIV envelope glyocoprotein/CD4 interactions - studies using recombinant vaccinia virus vectors; RNA binding assays for the regulatory proteins tat and rev; Cellular and cell-free assays for tat; Cellular assays for rev; DNA binding proteins interacting with the viral LTR; Nef; Vpu; Vif; Cellular assays for antiviral drugs; Inhibition of HIV by ribozymes and antisense oligonucleotides; Gene therapy approaches to the inhibition of HIV

About the Author

J. Karn is at MRC Laboratory of Molecular Biology, Cambridge.

"About this title" may belong to another edition of this title.

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In Home, with additional storage building. Located on Route 100, Readsboro Falls, Vermont.

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Falls Bookstore
VT, U.S.A.

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