High-Risk Breast Cancer: Diagnosis

Ragaz, Joseph & Irving M. Ariel (editors)

ISBN 10: 3540192921 / ISBN 13: 9783540192923

Published by Springer, 1989

About this Item

With 67 Figures and 40 Tables. 383 pages. Near fine to very good condition, no name inside. Light board wear - there is a light edge bump on the upper top and bottom edge. Includes essays by various experts on Epidemiology, Oncogense, Flow Cytometry, Tumor Kinetics, Receptors, Pathology, Mammography, Immunology, etc.

Seller Inventory # 18157

Bibliographic Details

• Title: High-Risk Breast Cancer: Diagnosis
• Publisher: Springer
• Publication Date: 1989
• Language: English
• ISBN 10: 3540192921
• ISBN 13: 9783540192923
• Binding: Hardcover
• Edition: First Edition.
• Condition: VG
• Seller catalogs:
  • Medicine and Health
  • RARE

About this title

Synopsis

The most meaningful reward to clinicians and researchers is the absence of recurrent malignancy in their patients. While in some patients the disease will be cured by resection alone, in other similarly staged cases the disease will recur despite adequate loco regional and systemic therapies. Hence, risk assessment is a complex issue with many related or unrelated prognostic factors determining outcome. The purpose of this volume is to review some of the most relevant prognostic factors of newly diagnosed breast cancer, focusing on fea­ tures determining the magnitude of risk. The ultimate value of establishing the significance of each prognostic factor in a given patient will be the resulting ability to plan individu­ alized therapies for patients at different risk of recurrence at the time of diagnosis. To secure the maximum benefit for high-risk patients, while avoiding undue toxicity in those with low-risk lesions, a well-integrated analysis of all known prognostic factors will be essential in the early postdiagnos­ tic period. In addition to well-established staging criteria such as axillary nodes, tumor size, receptors, scanning and radiographic examinations, the more sophisticated labora­ tory techniques, as discussed by several authors herein, will playa crucial role in risk assessment. Most of them, - ploidy determination, oncogenes, tumor markers, monoclonal anti­ bodies, growth factors, etc. -are presently available in only a minority of treatment centers.