Publication of 167 pages. The boards are a little shelf rubbed and minor marks. Internally the pages are clean and complete. The text is legible. The binding is excellent. GK. Our orders are shipped using tracked courier delivery services.

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Bibliographic Details

Title: Methods in Steroid Toxicology: Report of a workshop held in Bonn, Dec. 1970
Publisher: Geron-X, Inc
Publication Date: 1972
Language: English
ISBN 10: 0876720335
ISBN 13: 9780876720332
Binding: Hardcover
Edition: First Edition.
Condition: Very Good
Dust Jacket Condition: No Jacket

About this title

Synopsis

This symposium dealt with the problem of whether the methods used in steroid toxicology, applied both to research and clinical testing of steroids are still relevant and allow valid conclusions to be drawn regarding side effects in the human subject. Among the other subjects covered in this Symposium is the problem of whether the results obtained in long term toxicity studies of sexual hormones and their influence upon tumor growth in beagles can be related to man. The neuro-endocrine control mechanisims that exist in animals and man are quite different. Present toxicological methods have not taken into account sufficiently the differing sensitivity of the target tissues in man and animals; this applies equally to the differing mode of action of steroids, their pharmacokinetics and metabolism. The ultimate action of a hormone is dependent not only upon the absolute amount of the administered substance, but is considerably modified by steroid inter relationships as well as the time sequence in which the hormone is administered.

Language Notes

Text: English, German (translation)

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