The Periplasm

Provides a thorough, state-of-the-art review of the periplasm, the extracytoplasmic compartment found in gram-negative bacteria.• Details important aspects of the physiology of pathogenic microorganisms, a selection of current drug resistance strategies, and lipopolysaccharide biosynthesis.• Provides insights into the evolution of cellular compartments and their benefit to living organisms. • Discusses the basic biological functions of the periplasm and their physiological relevance, including protein transport, folding, and quality control; bioenergetics; solute transport; stress responses; cell division; and cell architecture. • Serves as a resource for medical practitioners and students of biology, microbiology, biochemistry, structural biology, and biotechnology