Pharmaceutical Applications of Raman Spectroscopy (Wiley Series on Technologies for the Pharmaceutical Industry)

Hardcover, xiv + 264pp + 4 pages of glossy colour plates. No title page; faint residue of a removed label inside the front board; mild internal creasing. Book is clean and bright with unmarked text, free of stamps, firmly bound. Boards show shelfwear and scratches, short corner creases. Issued without a dust jacket. -- Contents: 1. Introduction to Raman Spectroscopy (Yukihiro Ozaki and Slobodan Sasic) 1.1 History of Raman Spectroscopy 1.2. The Principle of Raman Spectroscopy 1.3 An Example of Simpel Raman Spectrum: Raman Spectrum of Water 1.4 Characteristics of Raman Spectroscopy 1.5 The Classic Theory of Raman Effect 1.6 The Quantum Theory of Raman Scattering 1.7 Cross Section 1.8 Relevance to Pharmaceuticals 1.9 Resonance Raman Effect 1.10 Instrumentation for Raman Spectroscopy 2. Quantitative Analysis of Solid Dosage Formulations by Raman Spectroscopy (Steven E.J.Bell) 2.1 Introduction 2.2 Quantitative Analysis 2.3 Instrumental Parameters 2.4 Experimental Considerations 2.5 Nonstandard Samples 2.6 Conclusions 3. Surface Enhanced Resonance Raman Scattering (W. Ewen Smith) 3.1 Theory 3.2 The Experimental Setup 3.3 Examples of SERS/SERRS Assays 4. Raman Spectroscopy for Identifying Polymorphs (Fred Laplant and Anne De Paepe) 4.1 Introduction of Polymorphism 4.2 Instrumental Methods of Polymorph Characterization 4.3 Polymorph Screening 4.4 Process Control 4.5 Polymorph Quantitation 4.6 Calibration Set and Sample Preparation 4.7 Quantitation 4.8 Intellectual Property 5. Raman Spectroscopy for Monitoring Real-time Processes in the Pharmaceutical Industry (Kevin L. Davis, Mark S. Kemper and Ian R. Lewis) 5.1 Introduction 5.2 A Brief History of Raman Spectroscopy 5.3 Basic Theory of Raman Spectroscopy 5.4 General Instrumentation for Raman Spectroscopy 5.5 The Choice-Dispersive or FT? 5.6 Process Analysis and PAT 5.7 Why Choose Raman as a PAT Tool? The Need for Raman 5.8 Data Analysis 5.9 Applications 5.10 Conclusions 6. Raman Chemical Imaging of Solid Dosage Formulations (Slobodan Sasic) 6.1 Methods for Chemical Imaging 6.2 Data Analysis 6.3 Experimental 6.4 Applications 7. In vivo Raman Confocal Microspectroscopy of Skin (Andre van der Pol, William M. Riggs and Peter J. Caspers) 7.1 Introduction 7.2 Applications 7.3 Summary and Discussion 8. Raman Microspectroscopy and Imaging of Active Pharmaceutical Ingredients in Cells (Jian Ling) 8.1 Introduction 8.2 Current Approaches to Drug Imaging 8.3 Raman Spectroscopy and Raman Imaging 8.4 Raman Microspectroscopy and Imaging for Drug Research 8.5 Raman Intensity, Fluorescence Background, and SNR 8.6 Techniques to Improve SNR in Raman Imaging 8.7 Enhanced Raman Images with Postprocessing 8.8 Raman Imaging of Intracellular Distribution of Paclitaxel in Living Cells 8.9 Raman Imaging of Intracellular Distribution of Sulindac Sulfide in Fixed Cells 8.10 Conclusions and Future Outlook; Index.…