A comprehensive and practical overview of the identification, conduct and analysis of optimal Phase II trial design. Series: Statistics in Practice. Num Pages: 254 pages, illustrations (black and white). BIC Classification: MBGR1; MBNS; MJCL. Category: (P) Professional & Vocational. Dimension: 160 x 236 x 16. Weight in Grams: 464. . 2014. 1st Edition. Hardcover. . . . .

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Bibliographic Details

Title: A Practical Guide to Designing Phase II Trials in Oncology
Publisher: John Wiley & Sons Inc
Publication Date: 2014
Language: English
ISBN 10: 1118570901
ISBN 13: 9781118570906
Binding: Hardcover
Edition: 1st Edition
Condition: New

About this title

Synopsis

How to identify optimal phase II trial designs

Providing a practical guide containing the information needed to make crucial decisions regarding phase II trial designs, A Practical Guide to Designing Phase II Trials in Oncology sets forth specific points for consideration between the statistician and clinician when designing a phase II trial, including issues such as how the treatment works, choice of outcome measure and randomization, and considering both academic and industry perspectives. A comprehensive and systematic library of available phase II trial designs is included, saving time otherwise spent considering multiple manuscripts, and real-life practical examples of using this approach to design phase II trials in cancer are given.

A Practical Guide to Designing Phase II Trials in Oncology:

Offers a structured and practical approach to phase II trial design
Considers trial design from both an academic and industry perspective
Includes a structured library of available phase II trial designs
Is relevant to both clinical and statistical researchers at all levels
Includes real life examples of applying this approach

For those new to trial design, A Practical Guide to Designing Phase II Trials in Oncology will be a unique and practical learning tool, providing an introduction to the concepts behind informed decision making in phase II trials. For more experienced practitioners, the book will offer an overview of new, less familiar approaches to phase II trial design, providing alternative options to those which they may have previously used.

About the Author

Sarah Rose Brown, Walter M. Gregory, Christopher J. Twelves, and Julia M. Brown, Clinical Trials Research Unit, University of Leeds, UK

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