The Scientific Sherlock Holmes: Cracking the Case with Science and Forensics

The Scientific Sherlock Holmes connects Holmes' vegetable poisons with concepts in botany, his use of fingerprinting with forensic science, and carbon monoxide poisoning and hemoglobin tests with concepts in chemistry, thus integrating the Holmes stories with all branches of science.

Jim O'Brien is Distinguished Professor Emeritus at Missouri State University. A lifelong fan of Holmes, O'Brien presented his paper "What Kind of Chemist Was Sherlock Holmes" at the 1992 national American Chemical Society meeting, which resulted in an invitation to write a chapter on Holmes the chemist in the book Chemistry and Science Fiction. O'Brien has since given over 120 lectures on Holmes and science. In 1996, O'Brien taught a college course on Holmes in London.