Other questions explored include the following: What is the appropriate population to study? What is the therapeutic window for hormone therapy and/or estrogen therapy? What are the appropriate formulations of HT and ET? What should be considered the most appropriate design for clinical trials that address the efficacy of HT/ET? What are appropriate surrogate markers of neurological decline/impairment? What are the best in vitro and in vivo models to address the efficacy of postmenopausal HT or ET?
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Meharvan Singh and James W. Simpkins are the authors of The Future of Hormone Therapy: What Basic Science and Clinical Studies Teach Us, Volume 1052, published by Wiley.
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