Metabolomics in Food and Nutrition (Woodhead Publishing Series in Food Science, Technology and Nutrition) - Hardcover

Hardcover

ISBN 10: 1845695127 ISBN 13: 9781845695125

Publisher: Woodhead Publishing, 2013

Synopsis

Metabolomics enables valuable information about the biochemical composition of foods to be rapidly obtained. Since the biochemical profile of food largely determines key food properties such as flavour and shelf life, the information gained using metabolomics-based methods will enable greater control of food quality and also help to determine the relationship between diet and health. Metabolomics in food and nutrition provides an overview of their current and potential use in the food industry.

Part one reviews equipment, methods and data interpretation in metabolomics including the use of nuclear magnetic resonance (NMR), statistical methods in metabolomics, and metabolic reconstruction databases and their application to metabolomics research. Part two explores applications of metabolomics in humans, plants and food. Chapters discuss metabolomics in nutrition, human samples for health assessments, and current methods for the analysis of human milk oligosaccharides (HMOs) and their novel applications. Further chapters highlight metabolomic analysis of plants and crops, metabolomics for the safety assessment of genetically modified (GM) crops, and applications of metabolomics in food science including food composition and quality, sensory and nutritional attributes.

With its distinguished editors and team of expert contributors, Metabolomics in food and nutrition is a technical resource for industrial researchers in the food and nutrition sectors interested in the potential of metabolomics methods and academics and postgraduate students working in the area.

• Provides an overview of the current and potential future use of metabolomics in the food industry
• Chapters focus on key applications and review the analytical methods used and the bioinformatics techniques involved in processing the results
• Discusses metabolomics in nutrition, human samples for health assessments, and current methods for the analysis of human milk oligosaccharides (HMOs) and their novel applications

About this title

About the Author:

Dr. Weimer's laboratory group focuses on microbial physiology and function. Research on host/microbe interactions has led to the elucidation of the competitive binding of beneficial bacteria to the gut epithelium and the resulting displacement of pathogenic bacteria such as salmonella. Using genomics and functional genomics - gene expression, metabolomics, proteomics, and metagenomics - Dr. Weimer's program examines the mechanisms of gene interplay to produce a specific phenotype and the metabolism involved in the process. The interplay between the host, the microbe, and the interdependent response is a key question for his program. The primary thrust of his program is the systems biology of biological processes important for bacterial growth, survival, and persistence.

Recent work has focused on the specifics of bacterial adhesion in the gut. By using the Caco 2 cell model, Dr. Weimer has explored the binding of specific bacterial strains, the competitive binding of beneficial and pathogenic bacteria, the discovery of the molecular mechanisms of adhesion, and the cellular signaling that takes place when bacteria adhere to the intestinal wall. In addition, the group has investigated the adhesion and competitive binding of bacteria grown on human milk oligosaccharides compared with lactose. The findings of this research will pave the way toward understanding the underlying mechanisms of the benefits of “good bacteria and how they modulate host immunity.

Carolyn M. Slupsky is an Associate Professor and Nutritionist at the Foods For Health Institute, University of California, Davis, USA.

About this edition

• Publisher: Woodhead Publishing
• Publication date: 2013
• ISBN 10: 1845695127
• ISBN 13: 9781845695125
• Binding: Hardcover
• Edition number: 1
• Number of pages: 264
• Editor: Weimer Bart C, Slupsky Carolyn