To a modern reader, the most striking and original aspect of the Fabrica is its heavy reliance on images. They were based on meticulous observation of dissected cadavers, and Vesalius married them clearly to his text, using an elaborate system of captions, cross references, and marginal annotations, which made them an integral part of his presentation. Furthermore, the illustrations were works of art in their own right; even the simplest far exceeded all previous anatomical images in clarity and detail (with the exception of some of the unpublished anatomical drawings of Leonardo da Vinci), and the more elaborate were extraordinary for their beauty and the imaginativeness of their conception.
Commentary by Katharine Park, essay on historiated initials.
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