Principles and Methods of Toxicology

xxiii, [1], 2270, [2] pages. Signed by contributor Michael R. Landauer on fep. Minor page creasing. Dr. Landauer was a co-author of chapter 18. Dr. Hayes is a toxicologist with over 35 years of experience in industry and academics. He is a Senior Science Advisor at Spherix Consulting, providing strategic, scientific and regulatory guidance. Dr. Hayes also holds appointments at the Harvard School of Public Health and with the School of Public Health, University of Massachusetts. Dr. Hayes was the Corporate Toxicologist for RJR Nabisco with responsibility for all regulatory and toxicology issues related to the safety of ingredients and food contact substances for food and drink products. Corporate Vice-President of Product Integrity at the Gillette Company, he had responsibility for the safety evaluation and regulatory compliance of a variety of consumer products, plant safety, environmental stewardship, and quality control. At Gillette, he was responsible for managing regulatory and toxicology issues worldwide. Extensively revised and updated with new chapters and an expanded glossary, this fifth edition of the classic text, Principles and Methods of Toxicology provides comprehensive coverage in a manageable and accessible format. New topics include 'toxicopanomics', plant and animal poisons, information resources, and non-animal testing alternatives. Emphasizing the cornerstones of toxicology-people differ, dose matters, and things change, the book begins with a review of the history of toxicology and followed by an explanation of basic toxicological principles, agents that cause toxicity, target organ toxicity, and toxicological testing methods including many of the test protocols required to meet regulatory needs worldwide. Each method or procedure is examined from the standpoint of technique and interpretation of data and discusses problems and pitfalls that may be associated with each. The addition of several new authors allow for a more diverse treatment of the expanding field of toxicology. Maintaining the high-quality information and organizational framework, Principles and Methods of Toxicology, Fifth Edition continues to be a valuable resource for the advanced practitioner as well as the new disciple of toxicology. Fifth Edition [stated]. First printing [stated].…