Items related to Medicinal Chemistry: A Biochemical Approach
Emphasizing the molecular action of drugs, this text incorporates recent findings from biochemical pharmacology along with the latest insights into the interactions of drugs with their receptors. It is organized by targets of drug action--endogenous messengers and their receptors, membranes, enzymes, and DNA, among others--and covers all drug groups and their therapeutic applications. This new edition has been thoroughly revised to provide expanded coverage of co-transmitters and neurohormones as well as adenosine receptors and calcium channel blockers. The chapter on drug distribution and metabolism has been extended, and the final chapter on principles of drug design outlines new methods, such as numerical techniques and computer graphics. Other new topics include atrial natriuretic factors, antiarrhythmic drugs, and DNA topoisomerase inhibitory mechanism of antitumor and antibacterial agents. The text is illustrated with hundreds of formulas and tables, and the index includes an extensive listing of drugs.
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About the Author:
"The third edition of this popular textbook remains unique, authoritative, comprehensive and readable. Through a systematic organization of drug targets, all the important human disease and major categories of drugs are discussed providing insights into drug mechanisms and approaches to drug discovery. I highly recommend this book."--Doody's
"...recognized for its readability and clear-honed pitch, as the authors delve deeply into the mechanical specifics of how drugs take action on the human body."--The Electric Review
Thomas Nogrady is at Concordia University.
Review:
"The third edition of this popular textbook remains unique, authoritative, comprehensive and readable. Through a systematic organization of drug targets, all the important human disease and major categories of drugs are discussed providing insights into drug mechanisms and approaches to drug discovery. I highly recommend this book."--Doody's
"...recognized for its readability and clear-honed pitch, as the authors delve deeply into the mechanical specifics of how drugs take action on the human body."--The Electric Review
"About this title" may belong to another edition of this title.
- PublisherOxford University Press
- Publication date1988
- ISBN 10 0195053680
- ISBN 13 9780195053685
- BindingHardcover
- Edition number2
- Number of pages542
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