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Chemical Mutagens: Principles and Methods for Their Detection: Volume 2 - Hardcover

 
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The best protection against environmental mutagens is to identify them before they ever come into general use. But it is always possible that some substance will escape detection and affect a large number of persons without this being realized until later generations. This article considers ways in which such a genetic emergency might be promptly detected. A mutation-detecting system should be relevant in that it tests for effects that are as closely related as possible to those that are feared. It should be sensitive enough to detect a moderate increase in mutation rate, able to discover the increase promptly before more damage is done, responsive to various kinds of mutational events, and designed in such a way as to maxi­ mize the probability that the Gause of an increase can be found. Methods based on germinal mutation necessarily involve enormous numbers of persons and tests. On the other hand, with somatic mutations the individual cell becomes the unit of measurement rather than the in­ dividual person. For this reason, I think that somatic tests are preferable to germinal tests, despite the fact that it is germinal mutations which are feared.

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ISBN 10:  1461589711 ISBN 13:  9781461589716
Publisher: Springer, 2012
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Hollaender, Alexander
Published by Springer, 1971
ISBN 10: 0306371022 ISBN 13: 9780306371028
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Hollaender, Alexander
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Hollaender, Alexander, Ed.
Published by Plenum Press, 1974
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Hollaender, Alexander
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ISBN 10: 0306371022 ISBN 13: 9780306371028
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De Serres, Frederick J; Hollaender, Alexander
Published by Plenum Press, New York ; London, 1980
ISBN 10: 0306371022 ISBN 13: 9780306371028
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Hardcover. Condition: Fine. Octavo in brown cloth, brown text on spine; illus.; pages 311-610, 24 cm. In English; from the library of Nobel laureate Dr. Donald A. Glaser, inventor of the bubble chamber; search keyword DGLSR for more collectible titles from the extensive Glaser library; volume 2 of 2. Fine copy with Dr. Glaser's private library spine label on spine tail; o/w cloth is clean; boards are free of bumps; pages are clean, crisp, bright and free of marks and creases; edges of leaves are clean; binding is tight and square; a well-cared-for copy. Seller Inventory # 86060

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