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Protein Misfolding, Aggregation and Conformational Diseases: Part A: Protein Aggregation and Conformational Diseases (Protein Reviews, 4) - Hardcover
Synopsis
This volume fills the gap in protein review and protocal literature while summarizing recent achievements in the understanding of the relationships between protein misfoldings, aggregation, and development of protein deposition disorders. It is devoted to the general questions of conformational disorders and includes discussion of involvement of such common factors as molecular chaperones, oxidative damage, proteasome, glycosoaminoglycans, serum amyloid protein P and several others in the development of different disorders. Some experimental techniques applicable for the visualization of protein deposition in vivo and in vitro are also present.
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From the Back Cover
Protein Misfolding, Aggregation, and Conformational Disease, is the first book to discuss significant achievements in protein structure-function relationships in the areas of biochemistry, molecular biology and molecular medicine. This volume summarizes recent achievements in the understanding of the relationships between protein misfolding, aggregation and development of protein deposition disorders. Research indicates that various human disorders, including most neurodegenerative diseases, systemic amyloidoses and many others, arise from the misfolding and aggregation of an underlying protein. Protein Misfolding, Aggregation and Conformational Diseases is an ideal book for biochemists, protein scientists, immunologists, pharmaceutical scientists, and molecular and cellular biologists.
Reviews
本書は、タンパク質の解説書や実験手順書の足りない部分を補うとともに、タンパク質の異常な折り畳み・凝集とタンパク質が沈着する疾患の発症との関係を探る研究の最新情報を纏めています.本書ではコンフォメーション病に対する全般的な疑問の解説に主眼を置いていますが、様々な疾患の発症に関わる共通要素――分子シャペロンや酸化的障害、プロテアソーム、グリコサミノグリカン、血清アミロイドPタンパクなど――についても論じます.また、タンパク質の沈着をin vivoやin vitroで視覚化する実験技術も紹介しています.
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Protein Misfolding, Aggregation and Conformational Diseases: Part A: Protein Aggregation and Conformational Diseases (Protein Reviews) (Volume 4A)
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Protein Misfolding, Aggregation And Conformational Diseases
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Protein Misfolding, Aggregation And Conformational Diseases
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Protein Misfolding, Aggregation and Conformational Diseases: Part A: Protein Aggregation and Conformational Diseases (Protein Reviews, 4)
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PROTEIN REVIEW VOLUME 4 :PROTEIN MISFOLDING AGGREGATION AND CONFORMATIONAL DISEASES
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Protein Misfolding, Aggregation and Conformational Diseases
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Protein Misfolding, Aggregation and Conformational Diseases: Part A: Protein Aggregation and Conformational Diseases (Protein Reviews, 4)
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