Provides an overview of common mechanistic, structural, and genetic features of this unusual class of proteins, and offers core biochemical and biological information related to individual serpins. Section I deals with the structural and mechanistic properties of serpins, their gene organization and location, and inhibition mechanisms. Part II examines individual serpin groups according to common features. Part III looks at serpin properties from a biological and physiological perspective, and at their role in cancer and Alzheimer's disease. Annotation c. by Book News, Inc., Portland, Or.
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