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Cancer Cell Lines Part 2 (Human Cell Culture, 2) - Hardcover

 
9780792358787: Cancer Cell Lines Part 2 (Human Cell Culture, 2)

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Continuous cell lines derived from human cancers are the mostwidely used resource in laboratory-based cancer research. The first 3 volumes of this series on Human Cell Culture are devoted to these cancer cell lines. The chapters in these first 3 volumes have a common aim. Their purpose is to address 3 questions offundamental importance to the relevanceof human cancer cell lines as model systems of each type of cancer: 1. Do the cell lines available accurately represent the clinical presentation? 2. Do the cell lines accurately represent the histopathology of the original tumors? 3. Do the cell lines accurately represent the molecular genetics of this type of cancer? The cancer cell lines available are derived, in most cases, from the more aggressive and advanced cancers. There are few cell lines derived from low grade organ-confined cancers. This gap can be filled with conditionally immortalized human cancer cell lines. We do not know why the success rate for establishing cell lines is so low for some types of cancer and so high for others. The histopathology of the tumor of origin and the extent to which the derived cell line retains the differentiated features of that tumor are critical. The concept that a single cell line derived from a tumor at a particular site is representative oftumors at that site is naïve and misleading.

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9780792362258: Cancer Cell Lines: Part 3: Leukemias and Lymphomas (Human Cell Culture, 3)

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ISBN 10:  079236225X ISBN 13:  9780792362258
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Published by Springer, 1999
ISBN 10: 0792358783 ISBN 13: 9780792358787
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ISBN 10: 0792358783 ISBN 13: 9780792358787
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Masters, John R. W.|Palsson, B.
Published by Springer Netherlands, 1999
ISBN 10: 0792358783 ISBN 13: 9780792358787
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Gebunden. Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Continuous cell lines derived from human cancers are the mostwidely used resource in laboratory-based cancer research. The first 3 volumes of this series on Human Cell Culture are devoted to these cancer cell lines. The chapters in these first 3 volumes hav. Seller Inventory # 5968989

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ISBN 10: 0792358783 ISBN 13: 9780792358787
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Buch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - Continuous cell lines derived from human cancers are the mostwidely used resource in laboratory-based cancer research. The first 3 volumes of this series on Human Cell Culture are devoted to these cancer cell lines. The chapters in these first 3 volumes have a common aim. Their purpose is to address 3 questions offundamental importance to the relevanceof human cancer cell lines as model systems of each type of cancer: 1. Do the cell lines available accurately represent the clinical presentation 2. Do the cell lines accurately represent the histopathology of the original tumors 3. Do the cell lines accurately represent the molecular genetics of this type of cancer The cancer cell lines available are derived, in most cases, from the more aggressive and advanced cancers. There are few cell lines derived from low grade organ-confined cancers. This gap can be filled with conditionally immortalized human cancer cell lines. We do not know why the success rate for establishing cell lines is so low for some types of cancer and so high for others. The histopathology of the tumor of origin and the extent to which the derived cell line retains the differentiated features of that tumor are critical. The concept that a single cell line derived from a tumor at a particular site is representative oftumors at that site is naïve and misleading. Seller Inventory # 9780792358787

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Bernhard Ø Palsson
Published by Springer Netherlands Nov 1999, 1999
ISBN 10: 0792358783 ISBN 13: 9780792358787
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Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Continuous cell lines derived from human cancers are the mostwidely used resource in laboratory-based cancer research. The first 3 volumes of this series on Human Cell Culture are devoted to these cancer cell lines. The chapters in these first 3 volumes have a common aim. Their purpose is to address 3 questions offundamental importance to the relevanceof human cancer cell lines as model systems of each type of cancer: 1. Do the cell lines available accurately represent the clinical presentation 2. Do the cell lines accurately represent the histopathology of the original tumors 3. Do the cell lines accurately represent the molecular genetics of this type of cancer The cancer cell lines available are derived, in most cases, from the more aggressive and advanced cancers. There are few cell lines derived from low grade organ-confined cancers. This gap can be filled with conditionally immortalized human cancer cell lines. We do not know why the success rate for establishing cell lines is so low for some types of cancer and so high for others. The histopathology of the tumor of origin and the extent to which the derived cell line retains the differentiated features of that tumor are critical. The concept that a single cell line derived from a tumor at a particular site is representative oftumors at that site is naïve and misleading. 396 pp. Englisch. Seller Inventory # 9780792358787

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