Some Aspects of Chromosome Structure and Function: Chromosome Structure and Function - Hardcover

 
9780792370574: Some Aspects of Chromosome Structure and Function: Chromosome Structure and Function

Synopsis

It was at the end of the 19th century that a Swiss biologist, Karl Nageli first proposed the existence of hereditary organelles that carried information from parent to offspring. Ensuing decades experienced vigorous studies that led to the development of discovery that chromosomes are indeed the carriers of genetic information. Subsequent studies, especially by Morgan and Bridges, established unequivocally the chromosome theory of inheritance. Today, the structure of chromosome is well established. At the physical level, eukaryotic chromosomes are composed of a single, linear, double helix of DNA. The elementary helical structure involves nucleosomes, comprised of histones around which the DNA is wrapped. A hierarchy of higher order of chromosomal architecture may possibly be responsible for the regulation of gene helical structures expression. The localized condensations of DNA constitute chromomeres. Uncoiled structures sometimes extending from chromomeres, which form loops, is the result of discontinuities in the regular coiling of the DNA in the chromosome.

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9789401003353: Some Aspects of Chromosome Structure and Function: Chromosome Structure and Function

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ISBN 10:  9401003351 ISBN 13:  9789401003353
Publisher: Springer, 2011
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