Items related to Physiology and Physiopathology of Adipose Tissue
The scientific advances in the physiology and pathophysiology of adipose tissue over the last two decades have been considerable. Today, the cellular and molecular mechanisms of adipogenesis are well known. In addition, adipose tissue is now recognized as a real endocrine organ that produces hormones such as the leptin acting to regulate food intake and energy balance in the central nervous system, a finding that has completely revolutionized the paradigm of energy homeostasis. Other adipokines have now been described and these molecules are taking on increasing importance in physiology and pathophysiology. Moreover, numerous works have shown that in obesity, but also in cases of lipodystophy, adipose tissue was the site of a local low-grade inflammation that involves immune cells such as macrophages and certain populations of lymphocytes. This new information is an important step in the pathophysiology of both obesity and related metabolic and cardiovascular complications. Finally, it is a unique and original work focusing on adipose tissue, covering biology and pathology by investigating aspects of molecular and cellular biology, general, metabolic, genetic and genomic biochemistry.
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About the Author:
Jean-Philippe Bastard is a researcher at Inserm Institute at Tenon Hospital in Paris, France and Vice-President of the AFERO, the French Society of Study and Research on Obesity. Bruno Fève is Professor of Endocrinology at the Saint-Antoine Hospital in Paris, France.
Review:
From the reviews:
“This book comprehensively reviews our current understanding of adipose tissue biology as well as perturbations in adipose tissue that occur in pathological states such as obesity and diabetes. ... This is an excellent resource for adipose tissue biologists and students in the field. ... this book also may be useful to scientists in associated disciplines who are interested in understanding the ramifications of altered adipose tissue mass and function on many disease states. ... a very credible resource for anyone interested in the field.” (Robert Michael Sargis, Doody's Book Reviews, March, 2013)"About this title" may belong to another edition of this title.
- PublisherSpringer
- Publication date2012
- ISBN 10 2817803442
- ISBN 13 9782817803449
- BindingPaperback
- Number of pages460
- EditorBastard Jean-Philippe, Fève Bruno
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