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Synopsis
Endotoxin detection and control is a dynamic area of applied science that touches a vast number of complex subjects. The intersection of test activities includes the use of an ancient blood system from an odd “living fossil” (Limulus). It is used to detect remnants of the most primitive and destructive forms of life (prokaryotes) as contaminants of complex modern systems (mammalian and Pharma).
Recent challenges in the field include those associated with the application of traditional methods to new types of molecules and manufacturing processes. The advent of “at will” production of biologics in lieu of harvesting animal proteins has revolutionized the treatment of disease. While the fruits of the biotechnology revolution are widely acknowledged, the realization of the differences in the means of production and changes in the manner of control of potential impurities and contaminants in regard to the new versus the old are less widely appreciated.
Endotoxin as an ancient, dynamic interface between lifeforms, provides a singular perspective from which to view the parallel development of ancient and modern organisms as well as the progress of man in deciphering the complexity of their interactions in his efforts to overcome disease."synopsis" may belong to another edition of this title.
About the Author
Kevin Williams graduated from Texas A&M in 1982 with a BS in Microbiology. From there spent 30 years at Eli Lilly in Indianapolis. After retirement he has been at Hospira, Lonza, GE, and now BioMerieux .
"About this title" may belong to another edition of this title.
- PublisherSpringer
- Publication date2019
- ISBN 10 3030171477
- ISBN 13 9783030171476
- BindingHardcover
- LanguageEnglish
- Edition number1
- Number of pages880
- EditorWilliams Kevin L.
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Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Endotoxin detection and control is a dynamic area of applied science that touches a vast number of complex subjects. The intersection of test activities includes the use of an ancient blood system from an odd 'living fossil' (Limulus). It is used to detect remnants of the most primitive and destructive forms of life (prokaryotes) as contaminants of complex modern systems (mammalian and Pharma).Recent challenges in the field include those associated with the application of traditional methods to new types of molecules and manufacturing processes. The advent of 'at will' production of biologics in lieu of harvesting animal proteins has revolutionized the treatment of disease. While the fruits of the biotechnology revolution are widely acknowledged, the realization of the differences in the means ofproduction and changes in the manner of control of potential impurities and contaminants in regard to the new versus the old are less widely appreciated.Endotoxin as an ancient, dynamic interface between lifeforms, provides a singular perspective from which to view the parallel development of ancient and modern organisms as well as the progress of man in deciphering the complexity of their interactions in his efforts to overcome disease. 884 pp. Englisch. Seller Inventory # 9783030171476
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Endotoxin Detection and Control in Pharma, Limulus, and Mammalian Systems
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Buch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - Endotoxin detection and control is a dynamic area of applied science that touches a vast number of complex subjects. The intersection of test activities includes the use of an ancient blood system from an odd 'living fossil' (Limulus). It is used to detect remnants of the most primitive and destructive forms of life (prokaryotes) as contaminants of complex modern systems (mammalian and Pharma).Recent challenges in the field include those associated with the application of traditional methods to new types of molecules and manufacturing processes. The advent of 'at will' production of biologics in lieu of harvesting animal proteins has revolutionized the treatment of disease. While the fruits of the biotechnology revolution are widely acknowledged, the realization of the differences in the means ofproduction and changes in the manner of control of potential impurities and contaminants in regard to the new versus the old are less widely appreciated.Endotoxin as an ancient, dynamic interface between lifeforms, provides a singular perspective from which to view the parallel development of ancient and modern organisms as well as the progress of man in deciphering the complexity of their interactions in his efforts to overcome disease. Seller Inventory # 9783030171476
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