Testosterone: Action - Deficiency - Substitution - Hardcover

Hardcover

ISBN 10: 354052763X ISBN 13: 9783540527633

Publisher: Springer, 1990

Synopsis

New developments in testosterone therapy are summarized here by internationally renowned experts. They review both basic and clinical knowledge in fourteen chapters. The book begins with the biochemistry of testosterone, its biosynthesis, metabolism and mechanisms of action in target organs. Three chapters deal with specific aspects of testosterone action, namely its role in spermatogenesis, its psychotropic effects and its effects on bones. Syndromes caused by androgen resistance are described in order to highlight the importance of properly functioning enzymes and receptors in the target organs. Causes and symptoms of male hypogonadism, the major indication for testosterone treatment, are described. Five chapters are devoted to the pharmacology, pharmacokinetics and clinical uses and abuses of testosterone preparations. The new transdermal testosterone application is described in detail. Side effects of testosterone treatment are reviewed. The possible role of androgens in the development of prostatic hypertrophy and carcinoma is discussed extensively since this question is of major concern to the clinician.

About this title

Book Description

This book provides a comprehensive, up-to-date reference on testosterone and other androgens, and their role in human physiology and pathology. It covers biosynthesis and mechanisms of action and reviews their effects on brain and behaviour, spermatogenesis, hair growth, bones, muscles, erythropoiesis, the cardiovascular system and lipids, erection, and the prostate. Therapeutic uses of testosterone preparations are carefully evaluated, including use in women, the aging male, and its abuse and detection in sport. The book reviews applications in male contraception, the role of 5a-reductase inhibitors and the controversial use of DHEA.

From the Back Cover

New developments in testosterone action and therapy are summarized here by internationally renowned experts. They review both basic and clinical knowledge in 20 chapters. This 2nd edition has been thoroughly revised and extended. The book presents the biochemistry of testosterone, its biosynthesis, metabolism and mechanisms of action in target organs. Effects on bones, muscles, lipids, hair, the prostate, and the brain are considered in separate chapters. Syndromes caused by androgen resistance are described in order to highlight the importance of properly functioning enzymes and receptors in the target organs. The pharmacology, pharmacokinetics and clinical uses and abuses of testosterone preparations are discussed in detail, and side effects of testosterone treatment are reviewed. This is the state-of-the-art book about testosterone action and therapy for endocrinologists, andrologists, urologists and pharmacologists.

Edition details

• Publisher: Springer
• Publication date: 1990
• Language: English
• ISBN 10: 354052763X
• ISBN 13: 9783540527633
• Binding: Hardcover
• Number of pages: 285
• Editor: Nieschlag Susan, Nieschlag Eberhard, Behre Hermann M.