Analysis of Single-Cell Data: ODE Constrained Mixture Modeling and Approximate Bayesian Computation (BestMasters) - Softcover

Book 26 of 91: BestMasters

Loos, Carolin

 
9783658132330: Analysis of Single-Cell Data: ODE Constrained Mixture Modeling and Approximate Bayesian Computation (BestMasters)

Synopsis

Carolin Loos introduces two novel approaches for the analysis of single-cell data. Both approaches can be used to study cellular heterogeneity and therefore advance a holistic understanding of biological processes. The first method, ODE constrained mixture modeling, enables the identification of subpopulation structures and sources of variability in single-cell snapshot data. The second method estimates parameters of single-cell time-lapse data using approximate Bayesian computation and is able to exploit the temporal cross-correlation of the data as well as lineage information. 

"synopsis" may belong to another edition of this title.

About the Author

Carolin Loos is currently doing her PhD at the Institute of Computational Biology at the Helmholtz Zentrum München. She is member of the junior research group „Data-driven Computational Modeling“. 

From the Back Cover

Carolin Loos introduces two novel approaches for the analysis of single-cell data. Both approaches can be used to study cellular heterogeneity and therefore advance a holistic understanding of biological processes. The first method, ODE constrained mixture modeling, enables the identification of subpopulation structures and sources of variability in single-cell snapshot data. The second method estimates parameters of single-cell time-lapse data using approximate Bayesian computation and is able to exploit the temporal cross-correlation of the data as well as lineage information.

Contents

  • Modeling and Parameter Estimation for Single-Cell Data
  • ODE Constrained Mixture Modeling for Multivariate Data
  • Approximate Bayesian Computation Using Multivariate Statistics

Target Groups

    Researchers and students in the fields of (bio-)mathematics, statistics, bioinformatics
  • System biologists, biostatisticians, bioinformaticians

The Author
Carolin Loos is currently doing her PhD at the Institute of Computational Biology at the Helmholtz Zentrum München. She is member of the junior research group „Data-driven Computational Modeling“.


"About this title" may belong to another edition of this title.

Other Popular Editions of the Same Title

9783658132354: Analysis of Single-Cell Data: ODE Constrained Mixture Modeling and Approximate Bayesian Computation

Featured Edition

ISBN 10:  3658132353 ISBN 13:  9783658132354
Publisher: Springer Spektrum, 2016
Softcover