New Principles in Developmental Processes

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9784431546337: New Principles in Developmental Processes
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During the last decade, modern technologies have made a revolutionary change in developmental biology. The molecular and cellular processes in live embryos can now be visualized thanks to technologies using fluorescent proteins. The whole genome information of a wide range of animal species has now become available, confirming the common principles that operate in every species. These and other advances in our understanding of the developmental processes during embryogenesis and tissue regeneration have put forward new principles. Those new principles will also be important in the stem cell biology, branched from developmental biology, in order to generate a particular tissue by manipulating stem cells. This book is planned to introduce these new principles to readers who are working in developmental biology and/or stem cell biology fields, with an emphasis on genetic and cellular processes.

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This book highlights representatives of emerging new principles in the developmental biology field, such as cell competition, tissue asymmetry, a farewell to classical germ layer theory, and various new insights into tissue morphogenesis and specification based on the most modern experimental approaches. A large-scale paradigm shift occurred in the last decade owing to innovations in powerful live imaging technologies, gene manipulation techniques in developing embryos, and in-depth understanding of signaling systems, among other advances. Comparison between different animal species also highlighted commonalities of underlying principles, which had not been previously recognized. This book represents important elements that caused that paradigm shift, showing typical examples of phenomena or experimental evidence. It has as its mission the highlighting of important problems that currently are being solved, that are yet to be solved, and that are even still emerging. In other words, this book looks to the future based on the most up-to-date knowledge.

The authors take an energetic, fresh approach to opening up new horizons, and their work here represents the leading edge of contemporary developmental studies of international repute. Readers―both students and established scientists in the biomedical field―will learn where we are, where the problems are, and which way to go in their understanding of the developmental processes. Stem cell sciences need a solid grounding in real developmental processes. The new principles presented in this book provide important suggestions for designing three-dimensional functional organs in vitro and in other forms, and thus will contribute significantly to the future of stem cell sciences and regenerative medicine.

About the Author:

Hisato Kondoh (PhD. Professor, Graduate School of Frontier Biosciences, Osaka University) Atsushi Kuroiwa (PhD. Professor, Graduate School Science, Nagoya University)

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Book Description Springer Verlag, Japan, Japan, 2014. Hardback. Condition: New. 2014 ed. Language: English . Brand New Book. During the last decade, modern technologies have made a revolutionary change in developmental biology. The molecular and cellular processes in live embryos can now be visualized thanks to technologies using fluorescent proteins. The whole genome information of a wide range of animal species has now become available, confirming the common principles that operate in every species. These and other advances in our understanding of the developmental processes during embryogenesis and tissue regeneration have put forward new principles. Those new principles will also be important in the stem cell biology, branched from developmental biology, in order to generate a particular tissue by manipulating stem cells. This book is planned to introduce these new principles to readers who are working in developmental biology and/or stem cell biology fields, with an emphasis on genetic and cellular processes. Seller Inventory # SPR9784431546337

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