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The Role of Apoptosis in Development, Tissue Homeostasis and Malignancy: Death from inside out - Softcover

 
9789401105545: The Role of Apoptosis in Development, Tissue Homeostasis and Malignancy: Death from inside out

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Synopsis

1 Death from inside out: an overview.- Death in Development.- 2 The ins and outs of programmed cell death during C. elegans development.- 3 Programmed cell death in Drosophila.- 4 Block of neuronal apoptosis by a sustained increase of steady-state free Ca2+ concentration.- 5 Apoptosis in the haemopoietic system.- 6 Programmed cell death and the control of cell survival.- Regulation of Death in Cancer Cells.- 7 Integrated control of cell proliferation and cell death by the c-myc oncogene.- 8 The role of the p53 protein in the apoptotic response.- Signals, Modulators and Effectors.- 9 Apoptosis regulated by a death factor and its receptor: Fas ligand and Fas.- 10 Insights from transgenic mice regarding the role of bcl-2 in normal and neoplastic lymphoid cells.- 11 Molecular mechanisms for B lymphocyte selection: induction and regulation of antigen-receptor-mediated apoptosis of mature B cells in normal mice and their defect in autoimmunity-prone mice.- 12 Fas-based d10S-mediated cytotoxicity requires macromolecular synthesis for effector cell activation but not for target cell death.- Clinical Applications.- 13 Life, death and genomic change in perturbed cell cycles.- 14 Apoptosis and cancer chemotherapy.- 15 Granulocyte apoptosis and the control of inflammation.

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Other Popular Editions of the Same Title

9789401042451: The Role of Apoptosis in Development, Tissue Homeostasis and Malignancy: Death from inside out

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ISBN 10:  9401042454 ISBN 13:  9789401042451
Publisher: Springer, 2012
Softcover