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8vo, pp. (xii), xxxi, (i), 429, (16) errata and index, (3) blank. Contemporary calf, spine with raised bands and gilt rules, red morocco label. Endpapers browned, and text very slightly browned, but a fine and fresh copy. Inscribed in a bold hand on the front endpaper: ?February, 1788. Cost, two shillings, and six pence, £ 2.6? ?In the wake of his son?s death [from smallpox], Kilpatrick advocated inoculation against smallpox through articles in the South-Carolina Gazette? In 1743 he published, in London, An Essay on Inoculation Occasioned by the Smallpox Being Brought into South Carolina in the Year 1738, assembled from his South-Carolina Gazette articles, which established him as a respected authority on inoculation? In 1746 he worked with Isaac Maddox, bishop of Worcester, in the foundation of the Middlesex County Hospital for the Smallpox, where the lower classes were inoculated free of charge. His Analysis of Inoculation (1754), was effectively a textbook of the practice and was widely cited? The work was translated into Dutch, German, and French and established his international reputation? (ODNB). Silverstein, A history of immunology, pp. 14?15. Rosen, A history of public health, p. 185: ?Partly through his influence?inoculation became a well-established practice.?
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