Design and Analysis of DNA Microarray Investigations.

Simon, R.M., Korn, E.L., McShane, L.M., Radmacher, M.D., Wright, G.W., Zhao, Y.

ISBN 10: 1441918027 / ISBN 13: 9781441918024

Published by New York, Springer., 2004

About this Item

X, 199 p. Softcover. Versand aus Deutschland / We dispatch from Germany via Air Mail. Einband bestoßen, daher Mängelexemplar gestempelt, sonst sehr guter Zustand. Imperfect copy due to slightly bumped cover, apart from this in very good condition. Stamped. Statistics for Biology and Health. Sprache: Englisch.

Seller Inventory # 6519FB

Bibliographic Details

• Title: Design and Analysis of DNA Microarray Investigations.
• Publisher: New York, Springer.
• Publication Date: 2004
• Language: English
• ISBN 10: 1441918027
• ISBN 13: 9781441918024
• Binding: Soft cover
• Seller catalogs:
  • Mathematik

About this title

Synopsis

Microarray analysis is a very active research area in biology and statistical genetics. This book presents modern methods at a level accessible to biologists.

From the Back Cover

This book is targeted to biologists with limited statistical background and to statisticians and computer scientists interested in being effective collaborators on multi-disciplinary DNA microarray projects. State-of-the-art analysis methods are presented with minimal mathematical notation and a focus on concepts. This book is unique because it is authored by statisticians at the National Cancer Institute who are actively involved in the application of microarray technology.

Many laboratories are not equipped to effectively design and analyze studies that take advantage of the promise of microarrays. Many of the software packages available to biologists were developed without involvement of statisticians experienced in such studies and contain tools that may not be optimal for particular applications. This book provides a sound preparation for designing microarray studies that have clear objectives, and for selecting analysis tools and strategies that provide clear and valid answers. The book offers an in depth understanding of the design and analysis of experiments utilizing microarrays and should benefit scientists regardless of what software packages they prefer. In order to provide all readers with hands on experience in data analysis, it includes an Appendix tutorial on the use of BRB-ArrayTools and step by step analyses of several major datasets using this software which is freely available from the National Cancer Institute for non-commercial use.

The authors are current or former members of the Biometric Research Branch at the National Cancer Institute.  They have collaborated on major biomedical studies utilizing microarrays and in the development of statistical methodology for the design and analysis of microarray investigations. Dr. Simon, chief of the branch, is also the architect of BRB-ArrayTools.