Drug-DNA Interactions: Structures and Spectra (Methods of Biochemical Analysis)

Nakamoto, Kazuo; Tsuboi, Masamichi; Strahan, Gary D.

ISBN 10: 0471786268 / ISBN 13: 9780471786269

Published by Wiley, USA, 2008

About this Item

9780471786269. Pictorial board hardcover, from closed pharmaceutical company library. Lending record shows this book has never been borrowed. 392 pages, index, illustrated with photographs, charts, tables and diagrams. Describes the types of structural and bonding information that can be obtained using specific physico-chemical methods and how to design new drugs, with fewer side effects. Detailed information about X-ray crystallography, NMR spectroscopy, molecular modeling, and optical spectroscopy such as UV-Visible absorption, fluorescence, circular dichroism (CD), flow linear dichroism (FLD), infrared (IR) and Raman spectroscopy. Contents as new clean, tight and bright.

Seller Inventory # 032566

Bibliographic Details

• Title: Drug-DNA Interactions: Structures and Spectra (Methods of Biochemical Analysis)
• Publisher: Wiley, USA
• Publication Date: 2008
• Language: English
• ISBN 10: 0471786268
• ISBN 13: 9780471786269
• Binding: Hardcover
• Condition: Fine
• Dust Jacket Condition: No Jacket
• Book Type: Book
• Seller catalogs:
  • Pharmaceutical Industry

About this title

Synopsis

Learn vital information about drug-DNA interactions from Drug-DNA Interactions: Structures and Spectra, the only comprehensive book written about this topic. Understand the types of structural and bonding information that can be obtained using specific physico-chemical methods and discover how to design new drugs that are more effective than current treatments and have fewer side effects. Find detailed information about X-ray crystallography, NMR spectroscopy, molecular modeling, and optical spectroscopy such as UV-Visible absorption, fluorescence, circular dichroism (CD), flow linear dichroism (FLD), infrared (IR) and Raman spectroscopy.

About the Author

Kazuo Nakamoto pioneered the use of metal isotopes to elucidate the involvement of metals in low-frequency vibrations in metallic complexes and was among the first to use matrix isolation techniques to prepare and characterize unstable specie. He is the author of Infrared and Raman Spectra of Inorganic and Coordination compounds, Fifth Edition (Wiley).

Masamichi Tsuboi studies DNA and RNA structures, drug-DNA interaction, protein conformation, protein-nucleic acid recognition, and virus structure using a variety of physicochemical and biomedical techniques including X-ray diffraction, UV-Visible, IR/Raman , and NMR spectroscopy.

Gary D. Strahan uses physico-chemical techniques to understand biological systems relevant to pharmaceutical discovery and agricultural and natural product analyses. His work has emphasized spectroscopic methods, NMR, and computational modeling to determine the structures and properties of multistranded DNA, drug-DNA complexes, carbohydrates, and other biomolecules, as well as metabonomic and chemometric studies.