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Bibliographic Details

Title: The Endoplasmic Reticulum (Perspectives CSHL)
Publisher: Cold Spring Harbor Laboratory Pr
Publication Date: 2023
Language: English
ISBN 10: 1621824373
ISBN 13: 9781621824374
Binding: hardcover
Edition: 2nd Edition
Condition: New

About this title

Synopsis

The endoplasmic reticulum (ER) is a network of membranes that folds, modifies, and transports proteins in eukaryotic cells. It also manufactures lipids and interacts extensively with other organelles, playing essential roles in cell growth and homeostasis.

Written and edited by experts in the field, this new collection from Cold Spring Harbor Perspectives in Biology provides a comprehensive update on advances in our understanding of the structure and multiple functions of the ER. The contributors examine how proteins enter the ER, the biogenesis of membrane proteins, and the role of the ER in protein sorting and quality control. In addition, they discuss how lipids are synthesized and transported to and from the ER.

The volume reviews the architecture of the ER and the ways in which it interacts with other organelles. The consequences for metabolic health and neurodegeneration are also considered. It is thus an essential reference for cell biologists, as well as physiologists and pathologists interested in understanding the role of the ER in disease.

About the Authors

Susan Ferro-Novick is Professor of Cellular and Molecular Medicine at the University of California, San Diego

Tom A. Rapoport is Professor of Cell Biology at Harvard Medical School

Randy Schekman is Professor of Cell Biology, Development and Physiology at University of California at Berkeley

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