Ehem. Bibliotheksexemplar mit Signatur und Stempel. GUTER Zustand, ein paar Gebrauchsspuren. Ex-library with stamp and library-signature. GOOD condition, some traces of use. L07825 9780121828097 Sprache: Englisch Gewicht in Gramm: 1160.

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Bibliographic Details

Title

GTPases regulating membrane dynamics. Methods in enzymology, 404.

Publisher

Amsterdam, Elsevier

Publication Date

2005

Language

English

ISBN 10

0121828093

ISBN 13

9780121828097

Binding

Hardcover

Edition

Online-Ausg.

Condition

Gut

Weight

1160 grams

Seller catalogs

AA Varia

About this title

Synopsis

GTPases that regulate the myriad of membrane fission events that facilitate the assembly and disassembly of COPII (Sar1), COPI (ARF) and clathrin coats (dynamin) involved in exocytic and endocytic trafficking pathways and mitochrondrial organization remain a major challenge for future investigations to understand membrane architecture of eukaryotic cells. This volume of MIE provides a comprehensive set of articles describing the use and application of state-of-the-art methodologies to identify and characterize these GTPases and their rapidly expanding list of regulators and effectors. Methodologies focused on biochemical, molecular and advanced imaging techniques provide a wealth of investigational tools for those currently in the field and those entering the field. Many of the methodologies are generally applicable to study of these GTPases in vitro and in vivo to elucidate function in regulation of cell proliferation and signaling in normal tissue and in disease.

*Comprehensive collection of GTPases (ARF, Sar1, Dynamin) GTPases involved in vesicle coat assembly and membrane fission
*Identification and characterization of GTPase GEFs, GAPs and effectors
*General methodologies to study GTPase function in vitro and in vivo

"About this title" may belong to another edition of this title.

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