Geometric, Feature- and Graph-based Analysis of Protein Structures

Language: English

Published by Südwestdeutscher Verlag Für Hochschulschriften Aug 2013, 2013

3838134796 / 9783838134796

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This item is printed on demand - Print on Demand Titel. Neuware -The structural comparison of whole proteins or protein binding sites is usually performed by making use of graphs. Even though graphs exhibit a lot of interesting and useful properties, the usage of other representations can come along with several benefits. In this book the representation of a protein binding site is tackled. Three representations are considered namely the geometric, the feature-based and the graph-based representation. For all three types, some completely new algorithms are developed and presented. Moreover, existing methods are adapted to the application of protein binding sites' comparison. In addition, algorithms for the construction of multiple structural alignments are presented as a structural counterpart to multiple sequence alignment. By considering four different types of experiments, namely classification, similarity retrieval, clustering and construction of structural alignments, strengths and weaknesses of the proposed methods are detected and discussed. In addition a hybrid approach is presented which combines the benefits of a feature-based and a geometric method leading to a significant speed-up while still holding very good results.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 404 pp. Englisch.

Seller Inventory # 9783838134796

Title
Geometric, Feature- and Graph-based Analysis of Protein Structures
Author
Thomas Fober
Publisher
Südwestdeutscher Verlag Für Hochschulschriften Aug 2013
Publication year
2013
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3838134796
ISBN 13
9783838134796
Item weight
620 grams
Dimensions
220x150x25 mm

buchversandmimpf2000

Emtmannsberg, BAYE, Germany

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