Title: The Microbiome in Cancer and Autoimmunity - Part B (Volume 395) (International Review of Cell and Molecular Biology, Volume 395)
Publisher: Academic Press
Publication Date: 2025
Language: English
ISBN 10: 0443317089
ISBN 13: 9780443317088
Binding: Hardcover
Condition: New

About this title

Synopsis

Microbiome in Cancer and Autoimmunity - Part B, Volume 395 offers a comprehensive exploration of the intricate relationship between the human microbiome and the development of cancer and autoimmune diseases. Delving into cutting-edge research and clinical insights, this groundbreaking work elucidates the role of microbial communities in influencing immune responses, disease pathways, and therapeutic outcomes. Specific chapters cover the Effect of Microbial Dysbiosis on Autoimmune-Associated Inflammation, Gut Microbiota and Systemic Immune Responses in Cancer, The role of microbiome in gastrointestinal cancer, Cancer and Microbiome-Targeted Therapies, Autoimmune disease and Microbiome Targeted Therapies, and the Effect of Diet and Lifestyle on Microbiome Composition.

Explores the interconnection of Microbiome with Cancer and Autoimmunity
Covers the complex relationship between the microbiome and the development, progression, and treatment of cancer and autoimmune diseases
Includes an analysis of the composition, diversity, and functions of microbial communities in influencing cancer and autoimmune conditions
Discusses how the microbiome influences immune responses, inflammation, and immune tolerance in the context of cancer and autoimmunity

About the Author

Manisha Singh, PhD, is a trained human and mouse immunologist and during the last 10 years, she has specialized in cancer immunology. The main focus of her work has been to increase the efficacy and understand the molecular mechanisms of various cancer immunotherapies. She is serving as the principal investigator on a 2-year grant ($545,486), having been funded by the US Department of Defense. Dr. Singh's current research is focused on understanding the role of inflammation in immune suppression and resistance to immunotherapy in cancer. Recently, she has submitted the NIH-R01 grant in which she proposed to study the role of IL-1α in immunotherapy induced resistance. She has published 24 peer-reviewed articles and many abstracts in prestigious journals such as Nature Communication, Journal of Immunology, and Journal of Clinical Investigator. Her work has been cited by several prestigious, peer-reviewed, international journals.

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