Peptide Nucleic Acids: Protocols and Applications.

Nielson, Peter and Michael Egholm:

ISBN 10: 1898486166 ISBN 13: 9781898486169

Published by Wymondham: Horizon, 1999

Language: English

Condition: Used - Very good Hardcover

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Bibliographic Details

Title

Peptide Nucleic Acids: Protocols and Applications.

Publisher

Wymondham: Horizon

Publication Date

1999

Language

English

ISBN 10

1898486166

ISBN 13

9781898486169

Binding

Hardcover

Condition

Very Good

Seller catalogs

Biology

About this title

Synopsis

Peptide Nucleic Acid (PNA) is an analogue of DNA in which the backbone is a pseudopeptide rather than a sugar. PNA mimics the behaviour of DNA and binds complementary nucleic acid strands. The neutral backbone of PNA results in stronger binding and greater specificity than normally achieved. In addition, the unique chemical, physical and biological properties of PNA have been exploited to produce powerful biomolecular tools, antisense and antigene agents, molecues and biosensors. Important new applications have emerged that could not be performed using oligonucleotides. This book contains state-of-the-art protocols and applications on all aspects of Peptide Nucleic Acids. Concepts are explained clearly and in practical terms and each chapter contains concise background information. Written by leading experts in the field, the book is an invaluable and complete reference work on this novel and exciting area. An essential text for all molecular biologists, biochemists, geneticists, biotechnologists and nucleic acid chemists wishing to keep up with the latest developments.

Review

This book continues the contribution of the first edition as a valuable introduction to the reader new to the field of PNA as well as a highly useful reference book for experienced researchers and scientists. This book is highly recommended for science, medical and academic libraries supoprting research activity in molecular biology. - E-Streams Vol. 8, No. 5 - May 2005

This books is an excellent guide to PNAs and I would recommend it highly for anyone wanting an up-to-date and detailed text on this technology. - Dr Helena Ward, Australian Journal of Medical Science, May 2005, Vol 26, No. 2

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