Potential HIV Reverse Transcriptase Inhibitors : Synthesis of Benzyloxy Substituted 4,6- Diarylpyrimidine as potential HIV Reverse Transcriptase Inhibitors

Language: English

Published by LAP Lambert Academic Publishing, 2012

3659184713 / 9783659184710

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nach der Bestellung gedruckt Neuware - Printed after ordering - The existence of CNS viral reservoirs is the main cause of recurrence of HIV infection after medication is withdrawn. This problem remains unsolved because of poor CNS penetration with the existing anti retroviral drugs. To meet the demand of crossing the blood-brain barrier (BBB) the compound should have polar surface area (PSA). PSA is defined as the surface area occupied by oxygen and nitrogen atoms and hydrogen atoms attached to these atoms. With this aspect in view, we calculated the PSA values of various substituent on the aryl rings in our aimed compounds and they were found within the prescribed limits so we proceeded with the synthesis of the compounds.

Seller Inventory # 9783659184710

Title
Potential HIV Reverse Transcriptase Inhibitors : Synthesis of Benzyloxy Substituted 4,6- Diarylpyrimidine as potential HIV Reverse Transcriptase Inhibitors
Author
Komal P. Patel
Publisher
LAP Lambert Academic Publishing
Publication year
2012
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3659184713
ISBN 13
9783659184710
Item weight
118 grams
Dimensions
22.00x15.00x0.40 cm

AHA-BUCH GmbH

Einbeck, Germany

5-star seller

AbeBooks seller since August 14, 2006

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