Therapeutic Targeting of RAS Mutant Cancers

Language: English

Published by Cambridge University Press Sep 2022, 2022

1009073648 / 9781009073646

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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Neuware - The KRAS oncogene is believed to be the most common single nucleotide variant oncogene in human cancer. Historically, efforts to target KRAS and the other RAS GTPases have struggled. More recently, efforts have focused on identifying and exploiting features unique to specific oncogenic mutations. This has led to the first FDA approval for a RAS targeted therapy. This new agent is a covalent inhibitor that reacts with the cysteine residue created by a codon 12 glycine to cysteine (G12C) mutation within KRAS. Mutant-specific strategies may also exist for other KRAS single nucleotide variants, and recent studies provide examples and mechanisms.

Seller Inventory # 9781009073646

Title
Therapeutic Targeting of RAS Mutant Cancers
Author
Kendra Paskvan
Publisher
Cambridge University Press Sep 2022
Publication year
2022
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
1009073648
ISBN 13
9781009073646
Item weight
64 grams
Dimensions
229x152x2 mm

AHA-BUCH GmbH

Einbeck, Germany

5-star seller

AbeBooks seller since August 14, 2006

Shipping rates from Germany to U.S.A.

Item7 to 10 business days5 to 7 business days
First itemUS$ 39.25US$ 50.46
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