Language: English
Published by CreateSpace Independent Publishing Platform, 2017
ISBN 10: 1545497540 ISBN 13: 9781545497548
Seller: GreatBookPrices, Columbia, MD, U.S.A.
Condition: As New. Unread book in perfect condition.
Language: English
Published by CreateSpace Independent Publishing Platform, 2017
ISBN 10: 1545497540 ISBN 13: 9781545497548
Seller: GreatBookPrices, Columbia, MD, U.S.A.
Condition: New.
Language: English
Published by CreateSpace Independent Publishing Platform, 2017
ISBN 10: 1545497540 ISBN 13: 9781545497548
Seller: GreatBookPricesUK, Woodford Green, United Kingdom
US$ 28.82
Quantity: Over 20 available
Add to basketCondition: As New. Unread book in perfect condition.
Language: English
Published by CreateSpace Independent Publishing Platform, 2017
ISBN 10: 1545497540 ISBN 13: 9781545497548
Seller: GreatBookPricesUK, Woodford Green, United Kingdom
US$ 29.21
Quantity: Over 20 available
Add to basketCondition: New.
Language: English
Published by Createspace Independent Publishing Platform, 2017
ISBN 10: 1545497540 ISBN 13: 9781545497548
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Quantity: Over 20 available
Add to basketPaperback / softback. Condition: New. This item is printed on demand. New copy - Usually dispatched within 5-9 working days.
Language: English
Published by Createspace Independent Publishing Platform, 2017
ISBN 10: 1545497540 ISBN 13: 9781545497548
Seller: CitiRetail, Stevenage, United Kingdom
US$ 33.25
Quantity: 1 available
Add to basketPaperback. Condition: new. Paperback. In living organisms, biological macromolecules are intrinsically flexible and naturally exist in multiple conformations. Modern electron microscopy, especially at liquid nitrogen temperatures (cryo-EM), is able to visualise biocomplexes in nearly native conditions and in multiple conformational states. The advances made during the last decade in electronic technology and software development have led to the revelation of structural variations in complexes and also improved the resolution of EM structures. Nowadays, structural studies based on single particle analysis (SPA) suggests several approaches for the separation of different conformational states and therefore disclosure of the mechanisms for functioning of complexes. The task of resolving different states requires the examination of large datasets, sophisticated programs, and significant computing power. Some methods are based on analysis of two-dimensional images, while others are based on three-dimensional studies. In this review, we describe the basic principles implemented in the various techniques that are currently used in the analysis of structural conformations and provide some examples of successful applications of these methods in structural studies of biologically significant complexes. This item is printed on demand. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.