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Language: English
Published by VDM Verlag Dr. Müller, 2009
ISBN 10: 3639159241 ISBN 13: 9783639159240
Seller: moluna, Greven, Germany
Kartoniert / Broschiert. Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Arnouk HilalHilal Arnouk, MD. PhD. has graduated from Roswell Park Cancer nInstitute and is currently a senior postdoctoral fellow at the nUniversity of Alabama at Birmingham. Research interests include ntumor immunotherapy, proteomi.
Language: English
Published by VDM Verlag Dr. Müller, 2009
ISBN 10: 3639159241 ISBN 13: 9783639159240
Seller: AHA-BUCH GmbH, Einbeck, Germany
Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Grp170 is a major molecular chaperone/stress protein resident in the ER. It is distantly related in sequence to both hsp110 and hsp70 families. Although most chaperones are intracellular proteins they can be modified into secretory proteins. Chaperones secreted into the tumor microenvironment can recruit professional APCs and promote antigen presentation and priming of T-lymphocytes. This book describes an approach to target grp170 to the tumor microenvironment, which results in tumor rejection mediated by an adaptive immune response that is CD8+ dependent and accompanied by an enhanced cellular immune response against a tumor-specific antigen. Furthermore, the secreted grp170 is shown to deliver full-length tumor antigens to the tumor microenvironment. This approach has the potential of being exploited clinically as a cancer-specific vaccine in tumors of various histological origins.
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Language: English
Published by Bod Third Party Titles, 2019
ISBN 10: 1789848628 ISBN 13: 9781789848625
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Add to basketHRD. Condition: New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.
Seller: PBShop.store US, Wood Dale, IL, U.S.A.
HRD. Condition: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.
Seller: PBShop.store US, Wood Dale, IL, U.S.A.
HRD. Condition: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.
Language: English
Published by Bod Third Party Titles, 2019
ISBN 10: 1789848628 ISBN 13: 9781789848625
Seller: PBShop.store US, Wood Dale, IL, U.S.A.
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Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware 72 pp. Englisch.
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Seller: moluna, Greven, Germany
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Add to basketGebunden. Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. KlappentextrnrnHarnessing the potential of the human body s own immune system to attack malignant tumor cells has been the goal of many scientific investigators in recent years, with advances in cancer biology and immunology enabling cancer immu.
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Add to basketGebunden. Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. KlappentextrnrnIn recent years, biological cancer therapies, including immunotherapy, have moved from the bench to mainstream medical treatments of several types of cancer. The success of these treatments relies on innovative approaches to speci.