Avdeef Alex (31 results)
- Hardcover
Seller: St Vincent de Paul of Lane County, Eugene, OR, U.S.A.St Vincent de Paul of Lane County
Contact seller5-star sellerCondition: Used - Good
US$ 59.99
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Condition: Good. hardcover 100% of proceeds go to charity! Good condition with all pages in tact. Item shows signs of use and may have cosmetic defects.
- Hardcover
Seller: PBShop.store UK, Fairford, GLOS, United KingdomPBShop.store UK
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US$ 172.26
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HRD. Condition: New. New Book. Shipped from UK. Established seller since 2000.
- Hardcover
Seller: Brook Bookstore On Demand, Napoli, NA, ItalyBrook Bookstore On Demand
Contact seller3-star sellerCondition: New
US$ 175.15
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Condition: new.
- Hardcover
Seller: GreatBookPrices, Columbia, MD, U.S.A.GreatBookPrices
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US$ 181.47
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Condition: New.
- Hardcover
Seller: GreatBookPrices, Columbia, MD, U.S.A.GreatBookPrices
Contact seller5-star sellerCondition: Used - As new
US$ 183.11
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Condition: As New. Unread book in perfect condition.
- Hardcover
Seller: GreatBookPricesUK, Woodford Green, United KingdomGreatBookPricesUK
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US$ 172.25
US$ 19.95 shippingShips from United Kingdom to U.S.A.Quantity: Over 20 available
Condition: New.
- Hardcover
Seller: GreatBookPricesUK, Woodford Green, United KingdomGreatBookPricesUK
Contact seller5-star sellerCondition: Used - As new
US$ 185.12
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Condition: As New. Unread book in perfect condition.
- Hardcover
Seller: Majestic Books, Hounslow, , United KingdomMajestic Books
Contact seller4-star sellerCondition: New
US$ 219.82
US$ 8.64 shippingShips from United Kingdom to U.S.A.Quantity: 3 available
Condition: New. pp. 744.
- Hardcover
Seller: Kennys Bookshop and Art Galleries Ltd., Galway, GY, IrelandKennys Bookshop and Art Galleries Ltd.
Contact seller5-star sellerCondition: New
US$ 236.39
US$ 12.08 shippingShips from Ireland to U.S.A.Quantity: Over 20 available
Condition: New. Explains how to perform and analyze the results of the latest physicochemical methods With this book as their guide, readers have access to all the current information needed to thoroughly investigate and accurately determine a compound's pharmaceutical properties and their effects on drug absorption. Num Pages:…698 pages, Illustrations. BIC Classification: MMG; TDCW. Category: (P) Professional & Vocational. Dimension: 236 x 164 x 43. Weight in Grams: 1154. . 2012. 2nd Edition. Hardcover. . . . .
- Hardcover
Seller: Romtrade Corp., STERLING HEIGHTS, MI, U.S.A.Romtrade Corp.
Contact seller5-star sellerCondition: New
US$ 250.46
Free ShippingShips within U.S.A.Quantity: 5 available
Condition: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.
- Hardcover
Seller: Books Puddle, New York, NY, U.S.A.Books Puddle
Contact seller4-star sellerCondition: New
US$ 246.77
US$ 3.99 shippingShips within U.S.A.Quantity: 3 available
Condition: New. pp. 744 2nd Edition.
- Hardcover
Seller: SMASS Sellers, IRVING, TX, U.S.A.SMASS Sellers
Contact seller4-star sellerCondition: New
US$ 259.91
Free ShippingShips within U.S.A.Quantity: 5 available
Condition: New. Brand New Original US Edition. Customer service! Satisfaction Guaranteed.
- Hardcover
Seller: Books From California, Simi Valley, CA, U.S.A.Books From California
Contact seller4-star sellerCondition: Used - Very good
US$ 265.32
US$ 4.99 shippingShips within U.S.A.Quantity: 1 available
hardcover. Condition: Very Good.
- Hardcover
Seller: Revaluation Books, Exeter, , United KingdomRevaluation Books
Contact seller5-star sellerCondition: New
US$ 269.38
US$ 19.95 shippingShips from United Kingdom to U.S.A.Quantity: 2 available
Hardcover. Condition: Brand New. 2nd edition. 768 pages. 9.25x6.25x1.75 inches. In Stock.
- Hardcover
Seller: Kennys Bookstore, Olney, MD, U.S.A.Kennys Bookstore
Contact seller5-star sellerCondition: New
US$ 282.03
US$ 10.50 shippingShips within U.S.A.Quantity: Over 20 available
Condition: New. Explains how to perform and analyze the results of the latest physicochemical methods With this book as their guide, readers have access to all the current information needed to thoroughly investigate and accurately determine a compound's pharmaceutical properties and their effects on drug absorption. Num Pages:…698 pages, Illustrations. BIC Classification: MMG; TDCW. Category: (P) Professional & Vocational. Dimension: 236 x 164 x 43. Weight in Grams: 1154. . 2012. 2nd Edition. Hardcover. . . . . Books ship from the US and Ireland.
Predicting Solubility of New Drugs : Handbook of Critically Curated Data for Pharmaceutical Research
- Hardcover
Seller: GreatBookPrices, Columbia, MD, U.S.A.GreatBookPrices
Contact seller5-star sellerCondition: New
US$ 337.60
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Condition: New.
- Hardcover
Seller: Books Puddle, New York, NY, U.S.A.Books Puddle
Contact seller4-star sellerCondition: New
US$ 336.26
US$ 3.99 shippingShips within U.S.A.Quantity: 4 available
Condition: New. 1st edition NO-PA16APR2015-KAP.
- Hardcover
Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH
Contact seller5-star sellerCondition: New
US$ 285.47
US$ 76.33 shippingShips from Germany to U.S.A.Quantity: 2 available
Buch. Condition: Neu. Neuware - Explains how to perform and analyze the results of the latest physicochemical methodsWith this book as their guide, readers have access to all the current information needed to thoroughly investigate and accurately determine a compound's pharmaceutical properties and their effects on drug absorpti…on. The book emphasizes oral absorption, explaining all the physicochemical methods used today to analyze drug candidates. Moreover, the author provides expert guidance to help readers analyze the results of their studies in order to select the most promising drug candidates.This Second Edition has been thoroughly updated and revised, incorporating all the latest research findings, methods, and resources, including:\* Descriptions and applications of new PAMPA models, drawing on more than thirty papers published by the author's research group\* Two new chapters examining permeability and Caco-2/MDCK and permeability and the blood-brain barrier\* Expanded information and methods to support pKa determination\* New examples explaining the treatment of practically insoluble test compounds\* Additional case studies demonstrating the use of the latest physicochemical techniques\* New, revised, and expanded database tables throughout the bookWell over 200 drawings help readers better understand difficult concepts and provide a visual guide to complex procedures. In addition, over 800 references serve as a gateway to the primary literature in the field, facilitating further research into all the topics covered in the book.This Second Edition is recommended as a reference for researchers in pharmaceutical R&D as well as in agrochemical, environmental, and other related areas of research. It is also recommended as a supplemental text for graduate courses in pharmaceutics.
- Hardcover
Seller: Majestic Books, Hounslow, , United KingdomMajestic Books
Contact seller4-star sellerCondition: New
US$ 349.09
US$ 8.64 shippingShips from United Kingdom to U.S.A.Quantity: 4 available
Condition: New.
Predicting Solubility of New Drugs : Handbook of Critically Curated Data for Pharmaceutical Research
- Hardcover
Seller: GreatBookPrices, Columbia, MD, U.S.A.GreatBookPrices
Contact seller5-star sellerCondition: Used - As new
US$ 360.74
US$ 2.64 shippingShips within U.S.A.Quantity: 10 available
Condition: As New. Unread book in perfect condition.
Predicting Solubility of New Drugs : Handbook of Critically Curated Data for Pharmaceutical Research
- Hardcover
Seller: GreatBookPricesUK, Woodford Green, United KingdomGreatBookPricesUK
Contact seller5-star sellerCondition: New
US$ 366.00
US$ 19.95 shippingShips from United Kingdom to U.S.A.Quantity: 10 available
Condition: New.
Predicting Solubility of New Drugs : Handbook of Critically Curated Data for Pharmaceutical Research
- Hardcover
Seller: GreatBookPricesUK, Woodford Green, United KingdomGreatBookPricesUK
Contact seller5-star sellerCondition: Used - As new
US$ 367.09
US$ 19.95 shippingShips from United Kingdom to U.S.A.Quantity: 10 available
Condition: As New. Unread book in perfect condition.
- Hardcover
Seller: Biblios, frankfurt am main, HESSE, GermanyBiblios
Contact seller4-star sellerCondition: New
US$ 377.57
US$ 11.45 shippingShips from Germany to U.S.A.Quantity: 4 available
Condition: New.
- Hardcover
Seller: Grand Eagle Retail, Bensenville, IL, U.S.A.Grand Eagle Retail
Contact seller5-star sellerCondition: New
US$ 387.98
Free ShippingShips within U.S.A.Quantity: 1 available
Hardcover. Condition: new. Hardcover. In pharmaceutical research, solubility plays a key part in the assessment of pharmacokinetic risks. Poor drug absorption, reduced efficacy, excessive metabolism, and adverse reactions are frequently related to issues of drug solubility. During early discovery research at pharmaceutical compa…nies, many thousands of molecules are considered. Most are rejected due to perceived unfavorable properties. Here the author uses the Wiki-pS0TM database, which forms the backbone of this unique handbook. Also discussed is the emerging class of therapeutically promising research molecules called PROTACs (proteolysis-targeting chimeras), showing a propensity for undruggable targets.FEATURES A comprehensive and unique listing of measured aqueous intrinsic solubility focusing on drug-like and drug-relevant molecules. The database can be used to predict the solubility of research pharmaceutical molecules. Includes downloadable files of the database (.csv format). The mining of the database can result in a better design of solubility assay protocols, leading to better quality of measurements. Artificial intelligence and Bayesian statistics will likely be key to this subject area in the future.Alex Avdeef has been an American Association of Pharmaceutical Scientists (AAPS) Fellow since 2014, a former visiting senior research fellow at Kings College London, and is the author of Absorption and Drug Development (2nd ed., Wiley, 2012). In 2021, the book was translated into Chinese, by translators affiliated with the China Food and Drug Administration. For nearly 50 years, he has been teaching, researching, and developing methods, instruments, and analysis software for the measurement of ionization constants, solubility, dissolution, and permeability of drugs. His accomplishments in the development of instrumentation include several well-known instruments that are or recently have been manufactured by leading companies in the instrument market, including Thermo Fisher Scientific, Sirius Analytical, and Pion Inc. He has over 200 technical publications in primary scientific journals and book chapters. He has written several comprehensive technical guides and is a co-inventor on six patents. He cofounded Sirius Analytical (UK) in 1989, pION Inc. (USA) in 1996, and founded inADME Research (New York City) in 2011. His other positions were at Orion Research, Syracuse University, UC Berkeley, and Caltech. The correct amount of solubility is a key part in the search for new drugs to tackle diseases. This handbook provides data analysis of published solubility measurements of FDA recently-approved drugs methodically searched in recent years. Artificial intelligence and Bayesian statistics will likely be key to this subject area in the future. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.
- Softcover
Seller: moluna, Greven, , Germanymoluna
Contact seller5-star sellerCondition: New
US$ 371.70
US$ 56.37 shippingShips from Germany to U.S.A.Quantity: Over 20 available
Condition: New.
- Hardcover
Seller: Revaluation Books, Exeter, , United KingdomRevaluation Books
Contact seller5-star sellerCondition: New
US$ 439.39
US$ 33.25 shippingShips from United Kingdom to U.S.A.Quantity: 1 available
Hardcover. Condition: Brand New. 2520 pages. 10.00x7.00x2.13 inches. In Stock.
Predicting Solubility of New Drugs : Handbook of Critically Curated Data for Pharmaceutical Research
- Hardcover
Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH
Contact seller5-star sellerCondition: New
US$ 464.30
US$ 88.42 shippingShips from Germany to U.S.A.Quantity: 1 available
Buch. Condition: Neu. Neuware - The correct amount of solubility is a key part in the search for new drugs to tackle diseases. This handbook provides data analysis of published solubility measurements of FDA recently-approved drugs methodically searched in recent years. Artificial intelligence and Bayesian statistics will likely… be key to this subject area in the future.
- Hardcover
Seller: AussieBookSeller, Truganina, VIC, AustraliaAussieBookSeller
Contact seller5-star sellerCondition: New
US$ 590.23
US$ 37.00 shippingShips from Australia to U.S.A.Quantity: 1 available
Hardcover. Condition: new. Hardcover. In pharmaceutical research, solubility plays a key part in the assessment of pharmacokinetic risks. Poor drug absorption, reduced efficacy, excessive metabolism, and adverse reactions are frequently related to issues of drug solubility. During early discovery research at pharmaceutical compa…nies, many thousands of molecules are considered. Most are rejected due to perceived unfavorable properties. Here the author uses the Wiki-pS0TM database, which forms the backbone of this unique handbook. Also discussed is the emerging class of therapeutically promising research molecules called PROTACs (proteolysis-targeting chimeras), showing a propensity for undruggable targets.FEATURES A comprehensive and unique listing of measured aqueous intrinsic solubility focusing on drug-like and drug-relevant molecules. The database can be used to predict the solubility of research pharmaceutical molecules. Includes downloadable files of the database (.csv format). The mining of the database can result in a better design of solubility assay protocols, leading to better quality of measurements. Artificial intelligence and Bayesian statistics will likely be key to this subject area in the future.Alex Avdeef has been an American Association of Pharmaceutical Scientists (AAPS) Fellow since 2014, a former visiting senior research fellow at Kings College London, and is the author of Absorption and Drug Development (2nd ed., Wiley, 2012). In 2021, the book was translated into Chinese, by translators affiliated with the China Food and Drug Administration. For nearly 50 years, he has been teaching, researching, and developing methods, instruments, and analysis software for the measurement of ionization constants, solubility, dissolution, and permeability of drugs. His accomplishments in the development of instrumentation include several well-known instruments that are or recently have been manufactured by leading companies in the instrument market, including Thermo Fisher Scientific, Sirius Analytical, and Pion Inc. He has over 200 technical publications in primary scientific journals and book chapters. He has written several comprehensive technical guides and is a co-inventor on six patents. He cofounded Sirius Analytical (UK) in 1989, pION Inc. (USA) in 1996, and founded inADME Research (New York City) in 2011. His other positions were at Orion Research, Syracuse University, UC Berkeley, and Caltech. The correct amount of solubility is a key part in the search for new drugs to tackle diseases. This handbook provides data analysis of published solubility measurements of FDA recently-approved drugs methodically searched in recent years. Artificial intelligence and Bayesian statistics will likely be key to this subject area in the future. Shipping may be from our Sydney, NSW warehouse or from our UK or US warehouse, depending on stock availability.
- Hardcover
- Print on Demand
Seller: Grand Eagle Retail, Bensenville, IL, U.S.A.Grand Eagle Retail
Contact seller5-star sellerCondition: New
US$ 207.60
Free ShippingShips within U.S.A.Quantity: 1 available
Hardcover. Condition: new. Hardcover. Explains how to perform and analyze the results of the latest physicochemical methods With this book as their guide, readers have access to all the current information needed to thoroughly investigate and accurately determine a compound's pharmaceutical properties and their effects on drug a…bsorption. The book emphasizes oral absorption, explaining all the physicochemical methods used today to analyze drug candidates. Moreover, the author provides expert guidance to help readers analyze the results of their studies in order to select the most promising drug candidates. This Second Edition has been thoroughly updated and revised, incorporating all the latest research findings, methods, and resources, including: Descriptions and applications of new PAMPA models, drawing on more than thirty papers published by the author's research groupTwo new chapters examining permeability and Caco-2/MDCK and permeability and the blood-brain barrierExpanded information and methods to support pKa determinationNew examples explaining the treatment of practically insoluble test compoundsAdditional case studies demonstrating the use of the latest physicochemical techniquesNew, revised, and expanded database tables throughout the book Well over 200 drawings help readers better understand difficult concepts and provide a visual guide to complex procedures. In addition, over 800 references serve as a gateway to the primary literature in the field, facilitating further research into all the topics covered in the book. This Second Edition is recommended as a reference for researchers in pharmaceutical R&D as well as in agrochemical, environmental, and other related areas of research. It is also recommended as a supplemental text for graduate courses in pharmaceutics. Explains how to perform and analyze the results of the latest physicochemical methods With this book as their guide, readers have access to all the current information needed to thoroughly investigate and accurately determine a compound's pharmaceutical properties and their effects on drug absorption. This item is printed on demand. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.
- Hardcover
- Print on Demand
Seller: Revaluation Books, Exeter, , United KingdomRevaluation Books
Contact seller5-star sellerCondition: New
US$ 243.96
US$ 19.95 shippingShips from United Kingdom to U.S.A.Quantity: 2 available
Hardcover. Condition: Brand New. 2nd edition. 768 pages. 9.25x6.25x1.75 inches. In Stock. This item is printed on demand.
