Bruix J Editor (2 results)
Malignant Liver Tumours: Basic Concepts and Clinical Management Falk Workshop
Berr, F. [Editor]; Bruix, J. [Editor]; Hauss, J. [Editor]; Wittekind, Ch. [Editor]; Wands, J. [Editor];
- Hardcover
Seller: Fireside Bookshop, Stroud, GLOS, United KingdomFireside Bookshop
Contact seller5-star sellerCondition: Used - As new
US$ 54.38
US$ 33.00 shippingShips from United Kingdom to U.S.A.Quantity: 1 available
Cloth. Condition: Like New. Like New. Type: Book Hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC), both increasing in incidence, have become a major topic of basic and clinical research as well as clinical practice in hepatology. Experts in the field update the current concepts on the carcinogenesis of HCC and CC such…as genetic alterations in the pathways of cell cycle and apoptosis regulation, the hypothesis of dedifferentiation of hepatocytes to the malignant phenotype vs that of activation of hepatic progenitor cells incapable of maturation (maturation arrest hypothesis). In spite of an increasing number of genetic alterations described in human HCC as well as cell regulatory pathways tested in experimental HCC models, the key hits causing progression of the cell cycle in imbalance with apoptosis, tissue invasive growth and metastatic potential of cell clones still remain elusive. Very powerful genomic and proteomic techniques are promising insights into the carcinogenesis of liver malignancies that will allow more efficient therapeutic strategies. The current concepts on risk profiling, surveillance of risk groups and therapeutic strategies are evidence-based for HCC and less detailed for CC. Surveillance of risk groups improves detection of liver tumours in curable stages. Best strategies for curative treatment of HCC use neoadjuvant antitumour therapies before liver transplantation and a role is emerging for living donor-related liver transplantation. New palliative therapies for HCC are in the experimental stage with biological response modifiers, including angiogenesis inhibitors, and entering phase II clinical trials with the alpha-fetoprotein derived vaccines.211pp.N.B.Slight fade mark to base of d/j spine.
Myocardium at Risk and Viable Myocardium: Evaluation by Spet
Candell-Riera, Jaume (Editor)/ Castell-Conesa, Joan (Editor)/ Aguade-Bruix, Santiago (Editor)
Language: English
Published by Kluwer Academic Pub 2001
Series: Developments in Cardiovascular Medicine, Book 194 of 253. Book 194 of 253 - Developments in Cardiovascular Medicine
- Hardcover
Seller: Revaluation Books, Exeter, , United KingdomRevaluation Books
Contact seller5-star sellerCondition: New
US$ 177.75
US$ 16.50 shippingShips from United Kingdom to U.S.A.Quantity: 2 available
Hardcover. Condition: Brand New. 1st edition. 244 pages. 10.00x6.75x0.75 inches. In Stock.
