Soft cover. Condition: Fine. No Jacket. 1st Edition. MATT STOKES: LOST IN THE RHYTHM, edited by Sarah Munro et al., softcover, first edition, illustrated with numerous color photos, 2007. BOOK CONDITION: fine. The text block and illustrations are in fine condition, with no tears, dogears, or marks. No bookplate or signature of a prior owner. Not a library book or remainder. The wraps are in fine condition. 9 x 6 3/4, 96 pages, 12 ounces XX (From the foreword and inner flaps) Unlike many artists steeped in modernist tradition and its conventions, Matt Stokes is part of a newer generation of artists whose extended practice involves a broader investigation of our culture. Stokes' practice is embedded in an anthropological inquiry of the broader subcultural movements that bring people together. His methodologies often lie in the development of collaborative and live elements, which arise through investigations into a range of factional and disparate communities connected to particular environments. By way of this process, he utilizes collaboration as a space for negotiation and appreciation of individual and group identities. His interest in collectivity, and creating connections between a location and an activity, is often anchored by music and its ability to shape both lifestyles and beliefs. For those who love music, it remains as a fixed point of reference, a source of reconciliation, exhilaration, and hope which never fails. Via his archaeological digs into the ephemera of underground cultures such as the Northern Soul scene and rave phenomenon, he has, like a cultural alchemist, created significant new works that transform our understanding in new ways. XX Matt Stokes lives and works in Newcastle upon Tyne. His practice is marked by anthropological enquiry and an interest in events or informal movements that bind people together. Music subcultures have been central to the development of his recent projects, which have focused on their ability to shape lifestyle, beliefs, and create collectivity. XX Essays by: Rob Tufnell is co-director of Ancient and Modern, London. Previously he has worked as a curator at Turner Contemporary in Margate, Kettle's Yard, Cambridge and Dundee Contemporary Arts. Matthew Collin is a journalist and the author of two books: Altered State, which charts the history of Ecstasy and dance culture, and This is Serbia Calling, about resistance to the government of Slobodan Milosevic in the former Yugoslavia. He has been editor of The Big Issue, Time Out website and i-D magazine, and currently works as a foreign correspondent for the BBC in Tbilisi, Georgia. Momus is an electronic folk musician and performance artist currently living in Berlin. His latest album is Ocky Milk, and he appeared as an Unreliable Tour Guide as part of the 2006 Whitney Biennial. He writes a regular column for Wired News about technology and society, and publishes daily 'pajamahadeen kulturkritik' on his blog, Click Opera.
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Buch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Following the implementation of next-generation sequencing technologies (e.g., exome and genome sequencing) in molecular diagnostics, the majority of genetic defects underlying inherited retinal disease (IRD) can readily be identified. In parallel, opportunities to counteract the molecular consequences of these defects are rapidly emerging, providing hope for personalized medicine. 'Classical' gene augmentation therapy has been under study for several genetic subtypes of IRD and can be considered a safe and sometimes effective therapeutic strategy. The recent market approval of the first retinal gene augmentation therapy product (LuxturnaTM, for individuals with bi-allelic RPE65 mutations) by the FDA has not only demonstrated the potential of this specific approach, but also opened avenues for the development of other strategies. However, every gene-or even every mutation-may need a tailor-made therapeutic approach, in order to obtain the most efficacious strategy with minimal risks associated. In addition to gene augmentation therapy, other subtypes of molecular therapy are currently being designed and/or implemented, including splice modulation, DNA or RNA editing, optogenetics and pharmacological modulation. In addition, the development of proper delivery vectors has gained strong attention, and should not be overlooked when designing and testing a novel therapeutic approach. In this Special Issue, we aim to describe the current state of the art of molecular therapeutics for IRD, and discuss existing and novel therapeutic strategies, from idea to implementation, and from bench to bedside.
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Add to basketGebunden. Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. KlappentextrnrnFollowing the implementation of next-generation sequencing technologies (e.g., exome and genome sequencing) in molecular diagnostics, the majority of genetic defects underlying inherited retinal disease (IRD) can readily be identi.
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Buch. Condition: Neu. Molecular Therapies for Inherited Retinal Diseases | Buch | Gebunden | Englisch | 2020 | MDPI AG | EAN 9783039431762 | Verantwortliche Person für die EU: Libri GmbH, Europaallee 1, 36244 Bad Hersfeld, gpsr[at]libri[dot]de | Anbieter: preigu Print on Demand.